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Table 4 Mortality associated with various antibiotic regimens in the treatment of V. cholerae non-O1, non-O139 (n=763a)

From: Antibiotic use for Vibrio infections: important insights from surveillance data

 

N

Crude mortality % (95% CI)

Comparison with Tetracycline alone FET p value

CDC treatment recommendation b

   

  Tetracycline alone

2/46

4.3 (1.2-14.5)

-

Other single antibiotics

   

  Quinolone alone

0/192

0.0 (0.0-2.0)

0.037

  Penicillin alone

1/38

2.6 (0.5-13.5)

1.000

  Cephalosporin alone

2/29

6.9 (1.9-22.0)

0.638

No antibiotic

25/270

9.3 (6.4-13.3)

0.395

  1. FET fisher’s exact test
  2. an=188 patients with less common antibiotic regimens not included here, thus numbers do not total to n=763
  3. bhttp://www.cdc.gov/cholera/treatment/antibiotic-treatment.html (accessed 27 June 2014): “Antibiotic choices should be informed by local antibiotic susceptibility patterns. In most countries, doxycycline is recommended as first-line treatment for adults, while azithromycin is recommended as first-line treatment for children and pregnant women”