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Table 2 Genotype and allele frequencies distribution of IL-23R polymorphisms between controls and cases

From: The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs

dbSNP ID/CNV

Genotype/Allele

Controls n (%)

PTB cases n (%)

OR (95 % CI)

rs1884444

TT

82 (33.1)

87 (34.8)

1

 

GT

122 (49.2)

114 (45.6)

0.88 (0.59–1.31)

 

GG

44 (17.7)

49 (19.6)

1.05 (0.63–1.74)

 

T

286 (57.7)

288 (57.6)

1

 

G

210 (42.3)

212 (42.4)

1.00 (0.78–1.29)

rs10889664

CC

93 (37.5)

103 (41.2)

1

 

CT

117 (47.2)

109 (43.6)

0.84 (0.57–1.23)

 

TT

38 (15.3)

38 (15.2)

0.90 (0.53–1.53)

 

C

303 (61.1)

315 (63.0)

1

 

T

193 (38.9)

185 (37.0)

0.92 (0.71–1.19)

rs11465788

TT

85 (34.7)

87 (34.9)

1

 

CT

120 (49.0)

114 (45.8)

0.93 (0.63–1.38)

 

CC

40 (16.3)

48 (19.3)

1.17 (0.70–1.96)

 

T

290 (59.2)

288 (57.8)

1

 

C

200 (40.8)

210 (42.2)

1.06 (0.82–1.36)

rs7518660

GG

105 (42.3)

33 (13.2)

1

 

AG

116 (46.8)

109 (43.6)

2.99 (1.87–4.79)

 

AA

27 (10.9)

108 (43.2)

12.73 (7.16–22.6)

 

G

326 (65.7)

175 (35.0)

1

 

A

170 (34.3)

325 (65.0)

3.56 (2.74–4.62)

rs11465802

CC

74 (30.0)

70 (28.0)

1

 

AC

121 (49.0)

121 (48.4)

1.06 (0.70–1.60)

 

AA

52 (21.0)

59 (23.6)

1.20 (0.73–1.97)

 

C

269 (54.5)

261 (52.2)

1

 

A

225 (45.5)

239 (47.8)

1.10 (0.85–1.41)

rs10889677

AA

76 (30.9)

57 (22.9)

1

 

AC

119 (48.4)

121 (48.6)

1.36 (0.89–2.08)

 

CC

51 (20.7)

71 (28.5)

1.85 (1.13–3.05)

 

A

271 (55.1)

235 (47.2)

1

 

C

221 (44.9)

263 (52.8)

1.37 (1.07–1.76)

CNV

CN < 2

3 (1.2)

7 (2.8)

2.66 (0.68–10.41)

 

CN = 2

230 (92.0)

202 (80.8)

1

 

CN > 2

17 (6.8)

41 (16.4)

2.75 (1.51–4.98)

  1. PTB pulmonary tuberculosis, OR odds ratio, CI confidence interval, CNV copy number variation, CN copy number