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Table 2 Sensitivity & Specificity compared to culture, stratified by HIV status

From: Chest radiograph reading and recording system: evaluation in frontline clinicians in Zambia

 

HIV Positive

HIV Negative

n = 30 culture-confirmed TB; 170 no TBa

n = 44 culture-confirmed TB; 259 no TB

 

Abnormalities consistent with TB

Any abnormality

Abnormalities consistent with TB

Any abnormality

 

Sensitivity

Specificity

Sensitivity

Specificity

Sensitivity

Specificity

Sensitivity

Specificity

CRRS-certified medical officers

 Reader 1

0.57

0.61

0.63

0.50

0.61

0.59

0.70

0.47

(0.37–0.75)

(0.53–0.68)

(0.44–0.80)

(0.42–0.58)

(0.45–0.76)

(0.53–0.65)

(0.54–0.83)

(0.41–0.54)

 Reader 2

0.50

0.60

0.50

0.59

0.55

0.61

0.55

0.60

(0.31–0.69)

(0.52–0.67)

(0.31–0.69)

(0.51–0.66)

(0.39–0.70)

(0.55–0.67)

(0.39–0.70)

(0.54–0.66)

CRRS-oriented clinical officers

 Reader 3

0.67

0.42

0.77

0.38

0.68

0.38

0.70

0.33

(0.47–0.83)

(0.34–0.50)

(0.58–0.90)

(0.31–0.46)

(0.52–0.81)

(0.32–0.44)

(0.55–0.83)

(0.27–0.39)

 Reader 4

0.53

0.37

0.53

0.35

0.61

0.37

0.61

0.33

(0.34–0.72)

(0.30–0.45)

(0.34–0.72)

(0.28–0.43)

(0.45–0.76)

(0.32–0.44)

(0.45–0.76)

(0.27–0.39)

  1. a33 HIV–positive and 35 HIV–negative participants excluded due to missing or contaminated cultures