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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity?

Fig. 2

Significantly differentially expressed genes during PZA-exposure. Numbers of genes up-regulated (in green) or down-regulated (in red), with a fold-change greater than two-fold and ANOVA p-value less than 0.05, in the early recovery phases (4 h after the addition of 100 μgml−1 PZA) and late recovery phases (2 mean generation times (MGT) after the addition of 100 μgml−1 PZA) compared to the pre-PZA phases under fast growth rates (23.1 h MGT) and slow growth rates (69.3 h MGT). The numbers shown in brackets refer to the subset of genes in each case that encode either tRNAs or ribosomal protein components

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