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Table 2 Plasma cytokine and chemokine levels among ATAHC participants with detectable HCV RNA at the time of acute HCV detection, stratified by HIV

From: HIV infection is associated with higher levels of monocyte chemoattractant protein-1 and eotaxin among people with recent hepatitis C virus infection

Cytokine

No HIV co-infection (n = 73)

HIV co-infection (n = 44)

P

IL-1 betaa

0.77 (0.77)

0.56 (0.59)

0.197

IL-2a

1.11 (0.12)

1.09 (0.13)

0.427

IL-4a

2.16 (0.25)

2.13 (0.28)

0.589

IL-6a

1.60 (0.63)

1.60 (0.64)

0.977

IL-8a

1.71 (0.54)

1.71 (0.48)

0.994

IL-10a

2.16 (0.66)

1.94 (0.72)

0.100

IL-17Aa

2.05 (0.53)

1.89 (0.70)

0.212

IL-17Fa

2.34 (0.49)

2.17 (0.56)

0.088

IL-18a

2.44 (0.29)

2.52 (0.25)

0.171

IL-21a

3.13 (0.55)

3.07 (0.56)

0.566

IL-22a

1.73 (0.68)

1.81 (0.53)

0.458

IL-23b

16 (22)

14 (32)

0.252

IL-25a

1.46 (0.72)

1.32 (0.94)

0.415

IL-31a

2.58 (0.51)

2.53 (0.61)

0.641

IL-33a

3.49 (0.26)

3.41 (0.29)

0.245

IFN-gammaa

2.62 (0.36)

2.68 (0.39)

0.417

IFN-gamma2b

57 (79)

38 (86)

0.329

TNF-alphaa

1.30 (0.47)

1.27 (0.47)

0.776

TNF-betab

68 (93)

43 (98)

0.407

TRAILa

2.07 (0.18)

2.12 (0.21)

0.119

sCD40La

2.89 (0.26)

2.90 (0.25)

0.865

CXCL10 (IP-10) a

2.98 (0.24)

3.11 (0.28)

0.013

CCL2 (MCP-1) a

1.98 (0.17)

2.10 (0.19)

<0.001

CCL3 (MIP-1a) b

36 (49)

16 (36)

0.172

CCL4 (MIP-1b) a

2.62 (0.24)

2.70 (0.32)

0.158

CCL5 (RANTES) a

3.78 (1.66)

3.94 (1.56)

0.606

CCL11 (eotaxin) a

1.62 (0.30)

1.79 (0.21)

<0.001

  1. a Presented as mean plasma level (standard deviation); log10 pg/mL
  2. b Presented as the number with undetectable plasma level (%)