Unadjusted model | Adjusted modela | |||
---|---|---|---|---|
Estimated mean differenceb (95 % CI) | P | Estimated mean differenceb (95 % CI) | P | |
HIV co-infection | ||||
Negative | Reference | Reference | ||
Positive | 0.13 (0.06, 0.19) | <0.001 | 0.11 (0.03, 0.18) | 0.009 |
Age, 10 years | 0.04 (0.00, 0.07) | 0.024 | 0.01 (−0.03, 0.05) | 0.575 |
Symptomatic acute HCV | ||||
No | Reference | |||
Yes | 0.06 (−0.01, 0.13) | 0.080 | ||
ALT level, log IU/L | 0.07 (0.00, 0.14) | 0.049 | 0.02 (−0.05, 0.10) | 0.502 |
Estimated duration of infection | ||||
<26 weeks | Reference | |||
≥26 weeks | −0.05 (−0.12, 0.02) | 0.196 | ||
Interferon lambda rs12979860 genotype | ||||
TT/CT | Reference | |||
CC | 0.01 (−0.06, 0.08) | 0.809 | ||
HCV RNA level | ||||
<400,000 IU/mL | Reference | Reference | ||
≥400,000 IU/mL | 0.05 (−0.02, 0.12) | 0.181 | 0.02 (−0.06, 0.10) | 0.623 |
HCV genotypec | ||||
Genotype 1 | Reference | |||
Genotype 3 | 0.00 (−0.07, 0.08) | 0.937 | ||
Other | 0.09 (−0.05, 0.23) | 0.222 |