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Table 2 Ninety-day mortality in incident Staphylococcus aureus bacteremia patients with versus without chronic heart failure (CHF)

From: Chronic heart failure and mortality in patients with community-acquired Staphylococcus aureus bacteremia: a population-based cohort study

 

Number

Mortality % (95 % CI)

Crude MRR (95 % CI)

Adjusteda MRR (95 % CI)

CHF

    

 Absent

2248

30.4 (28.6–32.4)

1.00 (ref.)

1.00 (ref.)

 Present

390

44.6 (39.8–49.7)

1.60 (1.36–1.89)

1.24 (1.04–1.48)

CHF-related conditions

    

 CHF absent

2248

30.4 (28.6–32.4)

1.0 (ref.)

1.0 (ref.)

 Cardiomyopathy

52

30.8 (20.1–45.2)

0.99 (0.60–1.62)

1.04 (0.63–1.72)

 Valvular heart disease

70

60.0 (48.8–71.4)

2.44 (1.79–3.34)

1.73 (1.26–2.38)

 Myocardial infarction

85

41.2 (31.6–52.4)

1.45 (1.04–2.05)

1.17 (0.83–1.65)

 Atrial fibrillation

66

50.0 (38.7–62.5)

1.81 (1.27–2.57)

1.21 (0.85–1.73)

 None of the above

117

41.0 (32.7–50.5)

1.46 (1.09–1.95)

1.12 (0.83–1.50)

CHF severityb

    

 CHF absent

2248

30.4 (28.6–32.4)

1.00 (ref.)

1.00 (ref.)

 Non-users

99

32.2 (24.1–42.5)

1.08 (0.76–1.54)

0.99 (0.69–1.42)

 Low dose (≤40 mg/day)

39

38.5 (25.3–55.5)

1.30 (0.78–2.16)

0.83 (0.50–1.40)

 Medium dose (41–80 mg/day)

82

42.7 (32.8–54.1)

1.52 (1.08–2.14)

1.13 (0.80–1.59)

 High dose (81–159 mg/day)

75

53.3 (42.6–64.9)

2.05 (1.49–2.83)

1.55 (1.11–2.14)

 Very high dose (≥160 mg/day)

95

54.7 (45.1–64.9)

2.10 (1.59–2.79)

1.62 (1.21–2.18)

Duration of CHF

    

 CHF absent

2248

30.4 (28.6–32.4)

1.00 (ref.)

1.00 (ref.)

  < 3 years

188

50.0 (43.1–57.3)

1.83 (1.48–2.27)

1.43 (1.14–1.78)

  ≥ 3- < 6 years

81

39.5 (29.8–51.0)

1.39 (0.98–1.99)

1.01 (0.71–1.46)

  ≥ 6- < 10 years

69

42.0 (31.4–54.5)

1.52 (1.05–2.21)

1.22 (0.84–1.78)

  ≥ 10 years

52

36.5 (25.1–51.1)

1.25 (0.79–1.97)

0.97 (0.61–1.54)

  1. CI confidence interval, MRR mortality rate ratio
  2. aAdjusted for age, sex, conditions included in the modified Charlson Comorbidity Index (excluding the condition in question), hypertension, alcohol related conditions, marital status, and antibiotic treatment within 30 days of admission
  3. bDefined by daily loop-diuretic dosage