Fig. 3

Different trends of chemokines throughout the disease were exhibited between mild and severe dengue patients. IP-10 (a) and MCP-1 (b) were higher in dengue patients compared with healthy controls. They displayed similar decreasing trends throughout the whole disease process. Significant differences of IP-10 and MCP-1 were noted between mild and severe dengue patients on day 8-10, with continually decreasing trends in mild patients but not in severe patients. IL-8 (c) was higher in severe patients than mild patients and showed decreasing trends as patients recovered. Levels of RANTES (d) and GRO-α (e) were lower in severe dengue patients. No difference of eotaxin-1 (f) and MDC (g) in dengue patients was observed compared to healthy controls