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Table 5 Index case, household and household contacts characteristics and their relation to incident tuberculosis among household contacts

From: A prospective longitudinal study of tuberculosis among household contacts of smear-positive tuberculosis cases in Lima, Peru

 

Bivariate GLMM analysis

Multivariate GLMM analysis

 

IRR

95%CI

IRR

95%CI

Index case characteristics

    

 Sex

    

  Female

1

   

  Male

0.7

0.5–1.0

-

 

 Age

    

  18–27

1.3

0.8–2.3

-

 

  28–37

1.6

0.8–2.9

-

 

  38–47

1.1

0.5–2.6

-

 

  >48

1

   

 Cough

    

  Yes

1

   

  No

0.5

0.1–1.8

-

 

 Time from symptoms to treatmenta

    

  0–30 days

1

 

1

 

  >30 days

1.9

1.3–2.8

1.8

1.2–2.7

 Smear positivity at diagnosisb

    

  scanty

0.2

0.02–1.4

0.2

0.03–1.7

  +/++

1

 

1

 

  +++

1.6

1.1–2.4

1.5

1.02–2.3

 Treatment type

    

  Drug sensitive

1

   

  Multidrug resistant

1.6

0.5–5.4

-

 

Household characteristics

    

 Past TB episodesc in the household

    

  Yes

1.2

0.6–2.1

-

 

  No

1

   

 Recent TB episodesd in the household

    

  Yes

1.2

0.5–2.8

-

 

  No

    

 Persons per room

1.01

0.9–1.1

-

 

Household contact characteristics

    

 Sex

    

  Female

1

 

1

 

  Male

1.5

1.1–1.9

1.4

1.1–1.9

 Age

    

  0–5

1.0

0.5–1.8

0.9

0.4–1.9

  6–19

1.7

1.1–2.6

1.2

0.7–2.3

  20–40

2.3

1.5–3.5

1.5

0.9–2.6

  >40

1

 

1

 

 Relationship

    

  Sibling

2.8

1.8–4.3

2.6

1.6–4.0

  Parent

0.9

0.5–1.6

1.1

0.5–2.3

  Partner

2.9

1.7–5.0

2.7

1.5–4.8

  Offspring

1.5

0.9–2.5

1.5

0.9–2.4

  Other

1

 

1

 
  1. GLMM generalized linear mixed models, IRR incidence rate ratio, CI confidence interval
  2. a = time from symptoms was calculated from the date the participant reported to start coughing until the date of treatment registered, bscanty = 1–9 acid fast bacilli (AFB) in 100 fields, +/++ = from 10 AFB in 100 fields to 10 AFB per field in at least 50 fields, +++ = more than 10 acid fast bacilli in at least 20 fields, c = a TB episode in a HHC more than two years before the diagnosis of the index case, d = a TB episode within the two year