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Table 3 Clinical manifestations of severe dengue according to serotype

From: Serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in Vitória, Brazil

Clinical manifestation DENV-1 DENV-2 DENV-4 All three serotypes
  n/N P-value n/N P-value n/N P-value n/N
Any neurological disorders (%) 1/17 (5.9) 1.00b 1/10 (10.0) 0.53b 0/5 (0) 1.00b 2/32 (6.3)
Any cardiac disorders (%) 1/17 (5.9) 1.00b 0/10 (0) 1.00b 0/5 (0) 1.00b 1/32 (3.1)
Any signs of plasma leakage (%) 6/14 (42.9) 0.90a 3/7 (42.9) 1.00b 2/4 (50.0) 1.00b 11/25 (44.0)
 Hemoconcentration (%) 2/14 (14.3) 0.35b 3/7 (42.9) 0.30b 1/4 (25.0) 1.00b 6/25 (24.0)
 Cavity effusion (%) 1/14 (7.1) 1.00b 0/7 (0) 1.00b 1/4 (25.0) 0.30b 2/25 (8.0)
 Hypoproteinemia (%) 3/14 (21.4) 0.23b 0/7 (0) 0.53b 0/4 (0) 1.00b 3/25 (12.0)
Any sign of hemorrhage (%) 12/16 (75.0) 0.69b 6/8 (75.0) 1.00b 2/5 (40.0) 0.29b 20/29 (69.0)
 Positive tourniquet test (%) 8/11 (72.7) 0.60b 3/4 (75.0) 1.00b 0/2 (0) 0.11b 11/17 (64.7)
 Hematuria (%) 1/11 (9.1) 1.00b 0/4 (0) 1.00b 1/2 (50.0) 0.23b 2/17 (11.8)
 Petechiae (%) 3/11 (27.3) 0.63b 3/5 (60.0) 0.27b 0/2 (0) 0.53b 6/18 (33.3)
 Menorrhagia (%) 0/11 (0) 0.39b 1/5 (20.0) 0.28b 0/2 (0) 1.00b 1/18 (5.6)
 Gingival bleeding (%) 2/12 (16.7) 1.00b 1/4 (25.0) 1.00b 0/2 (0) 1.00b 3/18 (16.7)
 Epistaxis (%) 1/11 (9.1) 0.52b 1/4 (25.0) 1.00b 1/2 (50.0) 0.33b 3/17 (17.6)
  1. aPearson chi-square test; bFisher’s exact chi-square test