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Table 3 Unadjusted associations between individual characteristics [n (%)] of children 6 months to <5 years (n = 263) or 5 to <18 years (n = 120), hospitalized with community-acquired pneumonia and length of stay (LOS) or intensive care unit (ICU) admission

From: Association of sputum microbiota profiles with severity of community-acquired pneumonia in children

  

LOS

ICU admission

<4 days

≥ 4 days

 

No

Yes

 

Characteristic

N (%)

(%)

(%)

P value

(%)

(%)

P value

Age 6 months to <5 years

Demographic

  Race/Ethnicity

   

0.35

  

0.64

  White

28 (10.6)

10.6

10.9

 

10.1

15.4

 

  Black

210 (79.8)

81.4

75.0

 

80.6

73.1

 

  Other

25 (9.5)

8.0

14.1

 

9.3

11.5

 

 Gender

   

0.87

  

0.67

  Female

121 (46.0)

45.7

46.9

 

45.6

50.0

 

  Male

124 (54.0)

54.3

53.1

 

54.4

50.0

 

Fall/winter season

157 (59.7)

59.3

60.9

0.82

60.7

50.0

0.29

 Environmental tobacco smoke exposure

27 (10.4)

11.8

6.3

0.21

9.9

15.4

0.32

 Medical History

  Asthma/reactive airway disease

126 (47.9)

44.7

57.8

0.07

46.8

57.7

0.29

  Chronic conditions other than asthma

63 (24.0)

22.1

29.7

0.22

23.6

26.9

0.71

  Prior antibiotics

59 (22.4)

22.6

21.9

0.90

22.4

23.1

0.93

  Pneumococcal vaccinea

256 (98.5)

98.5

98.4

0.97

98.7

96.0

0.29

 Respiratory virus positive

  RSV

110 (41.8)

42.7

39.1

0.61

43.9

23.1

0.04

  Rhinovirus

89 (33.8)

36.2

26.6

0.16

35.4

19.2

0.10

Age 5 to <18 years

Demographic

  Race/Ethnicity

   

0.81

  

0.73

  White

19 (15.8)

16.5

14.6

 

16.7

12.5

 

  Black

93 (77.5)

76.0

80.5

 

76.0

83.3

 

  Other

8 (6.7)

7.6

4.9

 

7.3

4.2

 

 Gender

   

0.05

  

0.16

  Female

50 (41.7)

35.4

53.7

 

38.5

54.2

 

  Male

70 (58.3)

64.6

46.3

 

61.5

45.8

 

 Fall/winter season

68 (56.7)

58.2

53.7

 

57.3

54.2

0.78

 Environmental tobacco smoke exposure

17 (14.2)

15.2

12.2

0.66

14.6

12.5

1.00

Medical History

  Asthma/reactive airway disease

77 (64.2)

73.4

46.3

0.003

64.6

62.5

0.85

  Chronic conditions other than asthma

29 (24.2)

19.0

34.2

0.07

20.8

37.5

0.09

  Prior antibiotics

23 (19.2)

16.5

24.4

0.30

19.8

16.7

0.73

  Pneumococcal vaccineb

91 (76.5)

83.5

62.5

0.01

80.2

60.9

0.05

Respiratory virus positive

  RSV

13 (10.8)

12.7

7.3

0.37

9.4

16.7

0.30

  Rhinovirus

59 (49.2)

55.7

36.6

0.05

46.9

58.3

0.32

  1. aReceipt of at least one or more doses prior to enrollment, missing data for 3 subjects. Bold indicates a significant P value of <0.05
  2. bReceipt of at least one or more doses prior to enrollment, missing data for 1 subject