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Table 2 Antimicrobial (beta lactam) susceptibility of the breakthrough viridans group streptococcal strains

From: Breakthrough viridans streptococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients receiving levofloxacin prophylaxis in a Japanese hospital

        

No. of isolates at each MIC, mg/L

Antimicrobial agent

No. of isolates tested

Susceptible range mg/L

No. of the susceptible strains

Resistant range mg/L

No. of the resistant strains

MIC50, mg/L

MIC90, mg/L

≤0.03

0.06 ≤0.06; CFPM

0.12

0.25 ≤0.25; CAZ

0.5

1

2

4

8

16

Penicillin

28

≤0.12

22 (79 %)

>4

0

0.06

0.25

8

9

5

3

2

0

1

0

0

0

Ceftazidime

22

NA

NA

NA

NA

0.5

2

   

5

7

7

1

0

2

0

Cefepime

22

≤1

21 (95 %)

>4

0

0.12

0.25

 

9

7

4

0

1

1

0

0

0

Meropenem

22

≤0.5

22 (100 %)

>1

0

≤0.03

0.12

17

2

2

1

0

0

    
           

≤0.25/4

0.5/4

1/4

2/4

4/4

8/4

>16/4

Piperacillin/tazobactam

22

≤8/4

22 (100 %)

>16/4

0

≤0.25/4

≤0.25/4

   

21

1

0

0

0

0

0

  1. MIC minimum inhibitory concentration, CFPM cefepime, CAZ ceftazidim, NA not available