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Table 1 Patient characteristics of SAB episodes according to pvl positivity

From: The Epidemiology of Staphylococcus aureus and Panton-Valentine Leucocidin (pvl) in Central Australia, 2006-2010

 

pvl Negative

pvl Positive

Total (94)

p-value

n (%)

n (%)

n (%)

 

Adult (36)

Paed (7)

Total (43)

Adult (39)

Paed (12)

Total (51)

  

Indigenous

30 (83.3 %)

7(100 %)

37 (86.1 %)

38 (97.4 %)

11 (91.7 %)

49 (96.1 %)

86 (91.5 %)

0.082

Age (range)

  

43.6 (0.42-95)

  

39.5 (3-76)

 

0.378

Male

22 (61.1 %)

3 (42.9 %)

25 (58.1 %)

25 (64.1 %)

8 (66.7 %)

33 (64.7 %)

58 (61.7 %)

0.514

RESIDENCE

 Remote

17/35a (48.6 %)

5 (71.4 %)

22/42a (52.4 %)

24 (61.5 %)

11 (91.7 %)

35 (68.6 %)

57 (61.3 %)

0.109

 Town Camp

6/35a (17.1 %)

1 (14.3 %)

7/42a (16.7 %)

11 (28.2 %)

0 (0 %)

11 (21.6 %)

18 (19.4 %)

0.552

 Alice Springs

10/35a (28.6 %)

1 (14.3 %)

11/42a (26.2 %)

3 (7.7 %)

1 (8.3 %)

4 (7.8 %)

15 (16.1 %)

0.017

 Nursing Home/Prison

2/35a (5.7 %)

0 (0 %)

2/42a (4.8 %)

1 (2.6 %)

0 (0 %)

1 (2.0 %)

3 (3.23 %)

0.447

STAPHYLOCOCCAL TYPING

 MecA

9 (25.0 %)

2 (28.6 %)

11 (25.6 %)

13 (33.3 %)

4 (33.3 %)

17 (33.3 %)

28 (29.8 %)

0.413

 ST93

1 (2.8 %)

0 (0 %)

2 (2.3 %)

20 (51.3 %)

4 (33.3 %)

24 (47.1 %)

25 (26.6 %)

<0.001

 ST93 or related

1 (2.8 %)

0 (0 %)

2 (2.3 %)

30 (76.9 %)

9 (75.0 %)

39 (76.5 %)

40 (42.6 %)

<0.001

FOCUS OF INFECTION

 SSTI

4 (11.1 %)

1 (14.3 %)

5 (11.6 %)

21 (53.9 %)

1 (8.3 %)

22 (43.1 %)

27 (28.7 %)

0.001

 Osteoarticular

5 (13.9 %)

2 (28.6 %)

7 (16.3 %)

5 (12.8 %)

10 (83.3 %)

15 (29.4 %)

22 (23.4 %)

0.134

 Pneumonia

3 (8.3 %)

1 (14.3 %)

4 (9.3 %)

6 (15.4 %)

0 (0 %)

6 (11.8 %)

10 (10.6 %)

0.700

 Endocarditis

3 (8.3 %)

0 (0 %)

3 (7.0 %)

0 (0 %)

0 (0 %)

0 (0 %)

3 (3.2 %)

0.055

 Line Related

9 (25.0 %)

0 (0 %)

9 (20.9 %)

2 (5.1 %)

0 (0 %)

2 (3.9 %)

11 (11.7 %)

0.011

ACQUISITION

 Community Acquired

10 (27.8 %)

6 (85.7 %)

16 (37.2 %)

27 (69.2 %)

12(100 %)

39 (76.5 %)

55 (58.5 %)

<0.001

 Healthcare Associated

25 (69.4 %)

1 (14.3 %)

26 (60.5 %)

12 (30.8 %)

0 (0 %)

12 (23.5 %)

38 (40.4 %)

<0.001

 Nosocomial

9 (25.0 %)

1 (14.3 %)

10 (23.3 %)

4 (10.3 %)

0 (0 %)

4 (7.8 %)

14 (14.9 %)

0.037

SEVERITY

 SIRS

22 (61.1 %)

5 (71.4 %)

27 (62.8 %)

2 (74.4 %)

9 (75.0 %)

38 (74.5 %)

65 (69.2 %)

0.220

 ICU admission

12 (33.3 %)

1 (14.3 %)

13 (30.2 %)

12 (30.8 %)

0 (0 %)

12 (23.5 %)

25 (26.6 %)

0.464

OUTCOME

 Surgery

7 (19.4 %)

2 (28.6 %)

9 (20.9 %)

21 (53.9 %)

12 (100 %)

33 (64.7 %)

42 (44.7 %)

<0.001

 30 day Mortality

4 (11.1 %)

1 (14.3 %)

5 (11.6 %)

2 (5.1 %)

0 (0 %)

2 (3.9 %)

7 (7.5 %)

0. 156

 12 month Mortality

10 (27.8 %)

1 (14.3 %)

11 (25.6 %)

5 (12.8 %)

0 (0 %)

5 (9.8 %)

16 (17.0 %)

0.055

  1. Note: ST93 related includes ST93, ST59 and ST121
  2. Abbreviations: pvl Panton Valentine Leucocidin gene, SSTI skin and soft tissue infection, SIRS systemic inflammatory response syndrome, ICU intensive care unit
  3. aThe residence for 1 adult patient was unable to be determined