Virus | Glycosylation sites in the HA globular head |
---|
63 | 122 | 126 | 133 | 144 | 165 | 246 |
---|
H3-0 (7 NGSs) | NCT | NES | NWT | NGT | NKS | NVT | NCT |
H3-1 (6 NGSs) | NCT | NES | NWT | NGT | NKA | NVT | NCT |
- Residues 63, 122, 126, 133, 144, 165, and 246 are located in the globular head of hemagglutinin (HA)
- H3-0 virus has seven potential asparagine (N)-linked glycosylation sites (NGSs) in the HA globular head
- H3-1 is the mutant virus lacking NGS in the HA globular head at position 144; the mutation is produced by introducing a single amino acid substitution, namely, Ser (S) to Ala (A), at residue 146 of H3-0. Thus, H3-1 virus has six potential NGSs in the HA globular head