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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG-mediated protection in a murine model of tuberculosis

Fig. 3

Protection conferred to infection with M. tuberculosis by BCG SSI and BCG Pasteur Aeras. Groups of 6 C57BL/6 mice were infected 6 weeks after immunization with BCG SSI (grey squares) or BCG Pateur Aeras (grey circles) via the intranasal route with 700 CFU M. tuberculosis Erdman. Control animals received saline at the time of immunization (open squares). CFUs per organ were determined 4 weeks after infection in lungs (a) and spleens (b). Each data point represents an individual animal. Error bars represent the median +/- interquartile range. Statistical significance was determined by one-way ANOVA with Holm-Sidak correction for multiple comparisons using GraphPad Prism

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