Split vaccine (n = 181) | Subunit vaccine (n = 190) | p-value | ||
---|---|---|---|---|
Solicited AE | (Event/subject) | 65/42 | 58/34 | 0.26/0.21 |
Systemic AE | (Event/subject) | 12/10 | 33/24 | 0.066/0.018 |
Fever/chill | 3 | 9 | 0.094 | |
Headache | 1 | 7 | 0.038 | |
Myalgia | 6 | 13 | 0.12 | |
Malaise | 2 | 4 | 0.45 | |
Local AE | (Event/subject) | 53/36 | 25/16 | 0.006/0.001 |
Pain | 31 | 14 | 0.004 | |
Erythema | 5 | 2 | 0.23 | |
Swelling | 9 | 9 | 0.92 | |
Unsolicited AE | 11 | 9 | 0.57 |