Fig. 5

Cytokine and Chemokine levels in CHPV infected human PBMC subsets. a Pro-inflammatory cytokine levels (IL-10, IL-8) in CHPV infected PBMC, CD14⁺cell, CD19⁺cell supernatant. b Pro-inflammatory cytokine levels (TNFα, IL-6, IL-1β) in CHPV infected PBMC, CD14⁺cell, CD19⁺cell supernatant and respective un infected cell control (CC) at 24 h post infection (pi). c Chemokine levels (CCL2, CCL5, CXCL9, CXCL10) in CHPV infected PBMC, CD14⁺cell, CD19⁺cell supernatant and respective un infected cell control (CC) at 24 h post infection. The box plot represents minimum, first quartile, median, third quartile and maximum. Total of 9 donors were used in the experiment. Statistical analysis was performed by Wilcoxon signed rank test. Paired test was applied to compare cytokine and chemokine levels among CHPV infected PBMC, CD14⁺cell, CD19⁺cell supernatant and respective uninfected cell control (CC). p value < 0.05 (*) significant, (**) 0.005 moderately significant and (***) 0.0005 highly significant among groups