Skip to main content

Table 1 Main characteristics of hyponatremic and normonatremic patients

From: Hyponatremia is a marker of disease severity in HIV-infected patients: a retrospective cohort study

Characteristics

Total (N = 1196)

Na < 135 mmol/l (N = 177)

Na ≥ 135 mmol/l (N = 1019)

P-value

Age (years)a

36.8 ± 10.7

37.4 ± 10.0

36.7 ± 10.9

0.238

Female gender (n)

445 (37.2%)

90 (50.8%)

355 (34.8%)

<0.0001

African ethnicity (n)

612 (51.2%)

125 (70.6%)

487 (47.8%)

<0.0001

Homo-bisexual orientation (n)

395 (33.0%)

26 (14.7%)

369 (36.2%)

<0.0001

Natremia (mmol/l)b

139.0 (136.0-141.0)

132.0 (130.0-134.0)

139.0 (137.0-141.0)

<0.0001

Hospitalization at first contact (n)

332 (27.7%)

128 (72.3%)

204 (20.0%)

<0.0001

Acquired immunodeficiency syndrome (AIDS) (n)

215 (18.0%)

89 (50.3%)

126 (12.4%)

<0.0001

CD4 cell count (/μl)a

371.8 ± 275.3

207.5 ± 197.7

400.4 ± 277.0

<0.0001

CD4 cell count < 350/μl (n)

611 (51.1%)

143 (80.8%)

468 (45.9%)

<0.0001

CD4 nadir (/μl)a

362.8 ± 267.6

200.8 ± 184.1

391.2 ± 269.9

<0.0001

CD4 nadir < 200/μl (n)

360 (30.1%)

106 (59.9%)

254 (24.9%)

<0.0001

HIV viral load (copies/ml)b

71600 (13500–100000)

100000 (55000–313500)

58750 (11800–100000)

<0.0001

HIV viral load > 100 000 copies/ml (n)

465 (38.9%)

104 (58.7%)

361 (35.4%)

<0.0001

Hepatitis B (n)

69 (5.8%)

14 (7.9%)

55 (5.4%)

0.223

Hepatitis C (n)

69 (5.8%)

12 (6.8%)

57 (5.6%)

0.478

Fib 4 score > 3.25 (n)

77 (6.4%)

28 (15.8%)

49 (4.8%)

<0.0001

Anemia (n)

597 (50%)

138 (78%)

459 (45%)

<0.0001

Hyperlipidemia (n)

418 (34.9%)

58 (32.8%)

360 (35.3%)

0.550

Mean triglyceridemia (mg/dl)a

111.1 ± 68.5

132.4 ± 79.9

108.0 ± 66.0

<0.0001

Mean estimated glomerular filtration ratec (ml/min)a

112.3 ± 23.3

111.4 ± 29.3

112.5 ± 22.0

0.227

Diabetes mellitus (n)

52 (4.3%)

14 (7.9%)

38 (3.7%)

0.0254

Antihypertensive drugs (n)

39 (3.3%)

4 (2.2%)

35 (3.4%)

0.645

  1. amean ± standard deviation
  2. bmedian (interquartile range)
  3. cestimated using CKD-EPI equation [36]