Table 2 Empirical antibiotic therapy in patients with a known status of empirical antibiotic therapy
Variable | Empirical antibiotic therapy | |
|---|---|---|
Appropriate (n = 3778) | Inappropriate (n = 1290) | |
Mono versus combination therapy | ||
Monotherapy | 1830 (48)a | 822 (64) |
Two antibiotics in combination | 1271 (34) | 339 (26) |
Three or more antibiotics in combination | 677 (18) | 129 (10) |
Beta-lactam antibiotics | ||
Penicillin | 601 (16) | 279 (22) |
Ampicillin | 263 (7) | 104 (8) |
Dicloxacillin | 49 (1) | 30 (2) |
Piperacillin/tazobactam | 225 (6) | 69 (5) |
Mecillinam | 91 (2) | 106 (8) |
Cefuroxime | 2168 (57) | 485 (38) |
Third generation cephalosporin | 152 (4) | 21 (2) |
Meropenem | 96 (3) | 48 (4) |
No beta-lactam | 133 (4) | 148 (11) |
Other antibiotics | ||
Gentamicin | 900 (24) | 101 (8) |
Ciprofloxacin | 538 (14) | 176 (14) |
Gentamicin & Ciprofloxacin | 13 (<1) | 3 (<1) |
Neither | 2327 (62) | 1010 (78) |
Metronidazole | 1008 (27) | 275 (21) |
Antifungal agent | 105 (3) | 49 (4) |