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Table 3 Frequency of deaths and crude mortality rates by age, sex and causes of death (1996-2012)

From: Changes in mortality rates and causes of death in a population-based cohort of persons living with and without HIV from 1996 to 2012

 

HIV-infected

HIV-uninfected

Deaths (%)

p-value

PY (per 1,000)

CMR per 1,000 PY (95% CI)

Deaths (%)

p-value

PY (per 1,000)

CMR per 1,000 PY (95% CI)

Age at cohort entry (years)

 20–34

873 (17.44)

<0.001

43.31

20.16 (18.82–21.50)

1,929 (0.78)

<0.001

2,321.61

0.83 (0.79–0.87)

 35–49

1,723 (25.92)

52.75

32.66 (31.12–34.21)

4,733 (3.50)

1,716.51

2.76 (2.68–2.84)

 50–64

582 (34.13)

11.24

51.78 (47.58–55.99)

9,639 (13.52)

916.26

10.52 (10.31–10.73)

 65+

223 (60.43)

1.7

131.37 (114.13–148.62)

31,346 (56.48)

556.77

56.30 (55.68–56.92)

Sex

 Male

2,716 (24.65)

0.529

88.76

30.60 (29.45–31.75)

24,394 (9.51)

<0.001

2,704.30

9.02 (8.91–9.13)

 Female

685 (25.26)

20.23

33.85 (31.32–36.39)

23,253 (9.16)

2,806.86

8.28 (8.18–8.39)

ARV ever?

 Yes

2,377 (23.38)

<0.001

90.95

26.14 (25.08–27.19)

    

 No

1,024 (28.73)

18.04

56.75 (53.28–60.23)

    

Cause of death

 All-cause

3,401 (24.77)

 

108.99

31.20 (30.16–32.25)

47,647 (9.34)

 

5,511.16

8.65 (8.57–8.72)

 HIV/AIDS-related

1,698 (12.37)

 

108.99

15.58 (14.84–16.32)

0 (0.00)

 

5,511.16

0.00 (0.00–0.00)

 Cancers

297 (2.16)

 

108.99

2.72 (2.42–3.03)

13,950 (2.73)

 

5,511.16

2.53 (2.49–2.57)

 Cardiovascular diseases

238 (1.73)

 

108.99

2.18 (1.91–2.46)

15,295 (3.00)

 

5,511.16

2.78 (2.73–2.82)

 Chronic respiratory diseases

52 (0.38)

 

108.99

0.48 (0.35–0.61)

2,179 (0.43)

 

5,511.16

0.40 (0.38–0.41)

 Drug abuse and overdose

380 (2.77)

 

108.99

3.49 (3.14–3.84)

696 (0.14)

 

5,511.16

0.13 (0.12–0.14)

 Hepatic and liver diseases

150 (1.09)

 

108.99

1.38 (1.16–1.60)

755 (0.15)

 

5,511.16

0.14 (0.13–0.15)

 Neurologic disorders

19 (0.14)

 

108.99

0.17 (0.10–0.25)

3,273 (0.64)

 

5,511.16

0.59 (0.57–0.61)

 Renal diseases

21 (0.15)

 

108.99

0.19 (0.11–0.28)

746 (0.15)

 

5,511.16

0.14 (0.13–0.15)

 Suicides

88 (0.64)

 

108.99

0.81 (0.64–0.98)

712 (0.14)

 

5,511.16

0.13 (0.12–0.14)

 Unintentional injuries

87 (0.63)

 

108.99

0.80 (0.63–0.97)

1,792 (0.35)

 

5,511.16

0.33 (0.31–0.34)

 Other infectious and parasitic diseases

101 (0.74)

 

108.99

0.93 (0.75–1.11)

1,998 (0.39)

 

5,511.16

0.36 (0.35–0.38)

 Other causes

270 (1.97)

 

108.99

2.48 (2.18–2.77)

6,251 (1.22)

 

5,511.16

1.13 (1.11–1.16)

  1. Legend: ARV Antiretroviral (drug), CI Confidence Intervals, CMR Crude mortality rate, PY Person-years