Table 2 Risk of bias in studies of active TB incidence comparing IGRA with TST in children, immunocompromised people and recently arrived people from countries with a high incidence of TB
First author, Year | Study Participation | Study Attrition | Prognostic Factor Measurement | Outcome/Construct Measurement | Study Confounding | Statistical Analysis and Reporting | Total ROB |
|---|---|---|---|---|---|---|---|
Children | |||||||
 Diel, 2011 [11] | Low | Low | Moderate | Moderate | Low | Low | Moderate ROB |
 Mahomed, 2011 [13] | Moderate | Moderate | Moderate | Moderate | High | Low | Moderate ROB |
 Metin Timur 2014 [14] | High | High | Moderate | Moderate | High | High | High ROB |
 Noorbakhsh 2011 [15] | High | High | High | Moderate | High | High | High ROB |
 Song, 2014 [16] | Low | Moderate | Low | High | Moderate | Low | Moderate ROB |
Immunocompromised | |||||||
 Elzi, 2011 [12] | High | Low | Low | Moderate | High | Low | High ROB |
 Kim, 2011 [17] | Low | Low | Low | Low | Moderate | Low | Low ROB |
 Kim, 2015 [18] | Low | Low | Low | Low | High | Low | Low ROB |
 Lee, 2009 [19] | High | Low | Low | Moderate | High | Low | High ROB |
 Lee, 2014 [22] | High | Moderate | Moderate | Moderate | Low | Low | Moderate ROB |
 Lee, 2015 [23] | Low | Low | Moderate | Low | High | Low | Low ROB |
 Milman, 2014 [20] | Low | Low | Moderate | Low | Low | Low | Low ROB |
 Moon, 2013 [21] | Moderate | Low | Moderate | Moderate | Moderate | Low | Moderate ROB |
 Sester, 2014 [24] | Low | Low | Moderate | Low | High | Low | Moderate ROB |
 Sherkat, 2014 [25] | High | High | Moderate | High | High | Moderate | High ROB |
Recent arrivals from countries with a high incidence of TB | |||||||
 Harstad, 2010 [26] | High | Low | High | Moderate | High | High | High ROB |
 Kik, 2010 [27] | Low | Low | Low | Low | Low | Low | Low ROB |