| |
Serum RPR titer <1:4
|
Serum RPR titer ≥1:4
|
|---|
|
Serum TPPA titer <1:2560
|
Serum TPPA titer ≥1:2560
|
Serum TPPA titer <1:2560
|
Serum TPPA titer ≥1:2560
|
|---|
|
Normal CK
|
Elevated CK
|
Normal CK
|
Elevated CK
|
Normal CK
|
Elevated CK
|
Normal CK
|
Elevated CK
|
|---|
|
S-NS
|
|
Female
|
1.0 (Ref.)
|
n.a.a
|
6.500
*
(1.273-33.201)
|
n.a.b
|
2.437 (0.502-11.845)
|
n.a.c
|
20.583
*
(5.853-72.380)
|
n.a.d
|
|
Male
|
1.264 (0.450-3.550)
|
3.900 (0.734-20.709)
|
9.286
*
(2.549-33.832)
|
9.750
*
(1.340-70.966)
|
4.643
*
(1.107-19.475)
|
6.500 (0.357-118.370)
|
53.300
*
(18.073-157.194)
|
n.a.d
|
|
Confirmed neurosyphilis
|
|
Female
|
1.0 (Ref.)
|
n.a.a
|
9.750 (0.507-187.526)
|
n.a.b
|
4.875 (0.275-86.351)
|
n.a.c
|
104.000
*
(11.575-934.402)
|
n.a.d
|
|
Male
|
1.083 (0.095-12.329)
|
n.a.e
|
n.a.e
|
39.000
*
(2.397-634.654)
|
11.143 (0.886-140.119)
|
n.a.e
|
265.200
*
(32.704-2150.534)
|
n.a.d
|
|
Probable neurosyphilis
|
|
Female
|
1.0 (Ref.)
|
n.a.a
|
5.850
*
(1.004-34.100)
|
n.a.b
|
1.950 (0.320-11.888)
|
n.a.c
|
3.900 (0.734-20.709)
|
n.a.d
|
|
Male
|
1.300 (0.427-3.959)
|
4.680 (0.849-25.811)
|
11.143
*
(2.913-42.620)
|
3.900 (0.297-51.196)
|
3.343 (0.647-17.267)
|
7.800 (0.419-145.200)
|
10.920
*
(3.176-37.549)
|
n.a.d
|
-
S-NS symptomatic neurosyphilis, N-NS syphilis/non-neurosyphilis, RPR rapid plasma reagin, TPPA T. pallidum particle agglutination, CK creatine kinase, OR odds ratio, Ref. reference, n.a. not applicable
-
*
P<0.05
-
aNo female patient with serum RPR titer <1:4, TPPA titer <1:2560 and elevated CK was in the S-NS group; the OR of S-NS was not applicable
-
bNo female patient with serum RPR titer <1:4, TPPA titer ≥1:2560 and elevated CK was in the N-NS group; the OR of S-NS was not applicable
-
cNo female patient with serum RPR titer ≥1:4, TPPA titer <1:2560 and elevated CK was in both groups; the OR of S-NS was not applicable
-
dIn both male and female patients, there was no one with serum RPR titer ≥1:4, TPPA titer ≥1:2560 and elevated CK in the N-NS group; the OR of S-NS was not applicable
-
eNo male patient with serum RPR titer <1:4, TPPA titer <1:2560 and elevated CK, or serum RPR titer <1:4, TPPA titer ≥1:2560 and normal CK, or serum RPR titer ≥1:4, TPPA titer <1:2560 and elevated CK was in the confirmed neurosyphilis subgroup; the OR of confirmed neurosyphilis was not applicable
