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Table 1 Analysis of the demographics and clinical data between late ART initiation and non-late ART initiation groups

From: Trends in baseline CD4 cell counts and risk factors for late antiretroviral therapy initiation among HIV-positive patients in Shanghai, a retrospective cross-sectional study

Characteristics

Total Patients (N = 3796)

Patients with late ART initiation (N = 2039)

Patients without late ART (N = 1757)

P-value

Age (Median, IQR)

35(29--48)

38(30--50)

33(27--44)

< 0.0001#

Age stratification

< 0.0001

  ≤ 30

1273(33.5)

567(28)

706(40.2)

 

 31–40

1058(27.9)

546(27)

512(29.1)

 

 41–50

704(18.6)

434(21)

270(15.4)

 

  ≥ 51

761(20)

492(24)

269(15.3)

 

Gender

0.10

 Male

3457(91)

1872(92)

1585(90.2)

 

 Female

339(9)

167(8)

172(9.8)

 

Marital status

< 0.0001

 Married or live together

1583(42)

945(46.3)

638(36)

 

 Single

1861(49)

876(43.0)

985(56)

 

 Divorced or separated

306(8)

189(9.3)

117(7)

 

 Widowed

46(1)

29(1.4)

17(1)

 

Infection routes

< 0.0001

 PWID

99(2.6)

59(2.9)

40(2.3)

 

 Homosexual

2073(54.6)

968(47.5)

1105(62.9)

 

 Heterosexual

950(25)

557(27.3)

393(22.4)

 

 Othersa

674(17.8)

455(22.3)

219(12.4)

 

CD4 cell counts

205(75--287)

88(25--162)

287(245.5--330.5)

< 0.0001#

WHO stage

0.24δ

 Stage I

15(0.4)

8(0.4)

7(0.4)

 

 Stage II

46(1.2)

14(0.7)

32(1.8)

 

 Stage III

2860(75.3)

1142(56)

1718(97.8)

 

 Stage IV

875(23.1)

875(42.9)

0(0)

 

Time to initiationb (months)

2(1--10)

1.5(1--6)

3(1.5--13)

< 0.0001#

Stratification of interval time

< 0.0001

  ≤ 3 months

2314(61)

1414(69)

900(51)

 3–12 months

674(18)

266(13)

408(23)

 

  > 12 months

808(21)

359(18)

449(28)

 

Year of ART initiation

< 0.0001

 2008

152(4)

121(5.9)

31(2)

 

 2009

254(6.7)

189(9.3)

65(4)

 

 2010

420(11.1)

257(12.6)

163(9)

 

 2011

601(15.8)

318(15.6)

283(16)

 

 2012

703(18.5)

375(18.4)

328(19)

 

 2013

1181(31.1)

561(27.5)

620(35)

 

 2014c

485(12.8)

218(10.7)

267(15)

 
  1. Results are shown as N (%) or the median (Q1--Q3)
  2. ART combined antiretroviral therapy, PWID people who inject drugs
  3. #By Mann-Whitney test
  4. aIncluding transmission via plasma donation (n = 2), mother-to-child transmission (n = 3), blood transmission (n = 55) and undetermined transmission (n = 614)
  5. δThis P value was detected by Chi-square analysis of the WHO stages I, II and stage III groups. The stage IV patients were not included
  6. bTime from the diagnosis of HIV to ART initiation
  7. cComprising data only from January 2014 to June 2014