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Table 3 Cost-effectiveness analysis of new diagnostic algorithms

From: Modeling the patient and health system impacts of alternative xpert® MTB/RIF algorithms for the diagnosis of pulmonary tuberculosis in Addis Ababa, Ethiopia

Diagnostic algorithms

DALYs averted per year

Additional health system costs per year over 10 years (US$)

Cost-effectiveness ratio (US$ per DALY averted)

YLL

YLD

DALY

ACER

ICER

ZN-Spot-Morning-Spot

0

0

0

   

FN-Spot-Morning-Spot

1935

25

1965

3456

2

Dominated

Targeted-Xpert-ZN-Negative-Spot-Morning-Spot

4660

64

4724

950669

201

Dominated

Targeted-Xpert- MDR-HIV-ZN-Spot-Morning-Spot

2838

39

2878

582813

203

Dominated

Full-Xpert

8988

128

9117

1161133

127

370.1

FN-Spot-Spot

4299

59

4358

-19748

-5

12.6

FN-Spot-Morning

1728

25

1747

-52727

-30

-30.2

Targeted-Xpert-MDR-HIV-FN-Spot-Spot

7256

104

7360

510831

69

176.7

  1. YLL years of life lost, YLD years lost due to disability, DALY disability adjusted life year. ACER average cost-effectiveness ratio, ICER incremental cost-effectiveness ratio