Table 1 Clinical and laboratory characteristics of the study group
Characteristics | Data | |
|---|---|---|
Number | 30 | |
Sex | Male (%)/female (%) | 14 (47)/16 (53) |
Age at liver biopsy (years) | Mean ± SD | 9.4 ± 3.7 |
Duration of infection (years) | Mean ± SD | 8.2 ± 3.1 |
BMI z-score | Mean ± SD | 0.39 ± 1.04 |
Mode of infection | Vertical (%) | 22 (73) |
Nosocomial (%) | 7 (23) | |
HCV genotype (%) | 1a | 2 (7) |
1b | 19 (63) | |
3 | 5 (17) | |
4 | 4 (13) | |
Viral load (IU/ml) | HCV median (IQR) | 5.95 × 105 (2.25 × 105–1.53 × 106) |
Laboratory findings Mean ± SD/median (IQR) | ALT (IU/l) | 60.5 (36–79) |
AST (IU/l) | 50 (37–68) | |
Platelets (× 109/l) | 308.2 ± 90.5 | |
METAVIR F | 0 | 8 (27) |
1 | 15 (50) | |
2 | 7 (23) | |
3–4 | 0 | |
Steatosis | Any (%) | 8 (27) |
Significant (%) | 4 (13) | |
APRI | Mean ± SD | 0.48 ± 0.26 |
FIB-4 | Mean ± SD | 0.22 ± 0.13 |
M-APRI | Mean ± SD | 0.28 ± 0.69 |
M-FIB-4 | Mean ± SD | 0.09 ± 0.28 |
B-AST | Mean ± SD | 31.71 ± 69.87 |