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Table 3 Comparison of clinical data for pneumonia-related characteristics in HAP patients with XDRAB and non-XDRAB

From: Pneumonia caused by extensive drug-resistant Acinetobacter baumannii among hospitalized patients: genetic relationships, risk factors and mortality

 

XDRAB

(N = 21)

N (%)

Non-XDRAB

(N = 42)

N (%)

P-value

Age, ya

77.5 ± 11.6

68.6 ± 18.4

0.023

Gender (M/F), n

17/4

23/19

0.079

APACHE II scorea

21.9 ± 6.8

18.0 ± 4.9

0.011

Related to hospitalizationa

18 (85.7)

30 (71.4)

0.347

 Days of mechanical ventilation before XDRAB (days)

10.5 ± 11.6

5.2 ± 5.8

0.059

 Hospital days before XDRAB (days)

18.3 ± 11.3

12.6 ± 11.2

0.064

 Length of stay in the ICU (days)

30.1 ± 20.0

21.4 ± 21.7

0.127

 Length of stay in the hospital (days)

45.5 ± 28.8

38.5 ± 24.2

0.199

Associated disease, n (%)

 COPD

13 (61.9)

9 (21.4)

0.001

 Diabetes mellitus

2 (9.5)

10 (40.4)

0.307

 Malignancy

2 (9.5)

9 (21.4)

0.411

 Cardiac disease

13 (61.9)

6 (14.2)

0.000

 Renal disease

5 (23.8)

2 (4.7)

0.065

 Neurological disease

8 (38.0)

22 (52.3)

0.422

Device, n (%)

 Urinary catheter

21 (100.0)

36 (85.7)

0.172

 Nasogastric tube

21 (100.0)

36 (85.7)

0.172

 Mechanical ventilation

16 (76.1)

31 (73.8)

1.000

Drug usage, n (%)

 Glucocorticoids

10 (47.6)

18 (42.8)

0.720

 PPIs

14 (66.7)

32 (76.1)

0.422

Antimicrobial n (%)

 Cephalosporin

   

  Second generation

3 (14.2)

5 (11.9)

1.000

  Third generation

7 (33.3)

18 (42.8)

0.649

 β-lactamase inhibitor

20 (95.2)

31 (73.8)

0.089

 Quinolone

13 (61.9)

19 (45.2)

0.327

 Aminoglycoside

2 (9.5)

4 (9.5)

1.000

 Carbapenem

11 (52.3)

11 (26.1)

0.040

 Antimicrobial Combination therapy, n (%)

11 (52.3)

19 (45.2)

0.593

Mortality, n (%)

9 (42.8)

15 (35.7)

0.582

  1. aValues are presented as the mean ± standard deviation; malignancy includes haematological malignancies and solid tumours; cardiac disease includes coronary artery disease, hypertensive heart disease, valvular disease and cardiomyopathy; renal disease includes chronic renal failure; neurological disease includes cerebral haemorrhage and cerebral infarction; PPIs proton pump inhibitor drugs