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Table 4 Associations between variables and HSV2 seropositivity in men, Germany 2008–2011

From: Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control

Variables

N

Weighteda prevalence %

(95% CI)

Univariable Analysis

Multivariable Analysis

PRb (95% CI)

p-value

PRc (95% CI)

p-value

Age group (years)

 18–24

222

1.2

(0.4–3.9)

Ref

Ref

Ref

Ref

 25–34

283

2.8

(1.4–5.3)

2.3 (0.6–9.0)

0.247

2.0 (0.5–7.8)

0.314

 35–44

343

4.3

(2.2–8.2)

3.5 (0.9-13.9)

0.075

3.1 (0.8–12.0)

0.100

 45–54

477

9.4

(6.3–13.8)

7.7 (2.5–24.0)

0.000

5.4 (1.7–17.1)

0.004

 55–64

418

11.4

(8.2–15.7)

9.3 (2.8–31.2)

0.000

6.9 (2.1–23.1)

0.002

 65+

685

11.0

(8.1–14.8)

9.0 (2.6–31.1)

0.001

d

d

CASMIN educational classification

 Low

806

8.7

(6.4–11.8)

1.1 (0.7–1.7)

0.768

−

−

 Medium

1069

5.7

(4.3–7.5)

0.7 (0.4-1.1)

0.109

−

−

 High

538

8.2

(5.8–11.4)

Ref

Ref

−

−

Income

 Low

656

6.1

(4.3–8.6)

Ref

Ref

−

−

 Medium

1414

7.2

(5.7–9.2)

1.2 (0.8–1.8)

0.374

−

−

 High

358

9.5

(6.1–14.4)

1.6 (0.9-2.8)

0.127

−

−

Employment situation

 Worker

844

7.9

(5.8–10.7)

1.0 (0.6–1.5)

0.890

−

−

 Employee

773

8.1

(6.0–10.9)

Ref

Ref

−

−

 Civil servant

183

7.0

(3.7–12.8)

0.9 (0.4–1.7)

0.659

−

−

 Free-lance/self-reliant

293

8.5

(5.6–12.5)

1.0 (0.6–1.8)

0.880

−

−

 Family worker

4

−

−

−

−

−

−

 Other

64

0.9

(0.1–6.5)

0.1 (0.1–0.1)

0.031

−

−

Smoking, currently

 Daily

524

6.3

(4.3–9.2)

0.9 (0.6–1.5)

0.761

−

−

 Occasionally

151

3.8

(1.7–8.2)

0.6 (0.2-1.3)

0.182

−

−

 No, not anymore

899

9.0

(6.8–11.7)

1.3 (1.0-1.8)

0.089

−

−

 Never smoked

843

6.8

(5.1–9.0)

Ref

Ref

−

−

Number of other children in household during childhood

 0

257

5.5

(3.2–9.3)

Ref

Ref

−

−

 1–2

999

5.8

(4.3–7.9)

1.1 (0.6–1.9)

0.839

−

−

  > 2

1172

8.9

(7.2–11.1)

1.6 (0.9-2.8)

0.087

−

−

Visit of nursery during childhoodd

 No

561

10.8

(7.9–14.5)

2.4 (1.7–3.5)

0.000

1.5 (1.0–2.2)

0.036

 Yes

1153

4.4

(3.4–5.8)

Ref

Ref

Ref

Ref

HSV1 serostatus

 HSV1 seronegative

548

6.5

(4.6–9.0)

Ref

Ref

−

−

 HSV1 seropositive

1880

7.4

(6.0–9.1)

1.1 (0.8–1.7)

0.494

−

−

Degree of urbanization

 Rural

435

6.5

(3.2–12.6)

Ref

Ref

−

−

 Provincial

620

6.1

(3.9–9.4)

0.9 (0.4–2.1)

0.875

−

−

 Urban

712

7.7

(5.7–10.3)

1.2 (0.6–2.5)

0.660

−

−

 Metropolitan

661

7.9

(6.2–10.2)

1.2 (0.6–2.5)

0.582

−

−

Region of residence

 West Germany

1675

6.6

(5.2–8.4)

Ref

Ref

−

−

 East Germany (including Berlin)

753

9.2

(7.0–11.9)

1.4 (1.0-2.0)

0.070

−

−

German mother tongue

 Yes

151

7.4

(6.1–8.9)

Ref

Ref

−

−

 No

2256

5.7

(3.2–9.9)

0.8 (0.4–1.4)

0.394

−

−

Number of sexual partners in last 12 months

 None

486

8.3

(5.5–12.3)

1.1 (0.7–1.8)

0.594

−

−

 1

1613

7.3

(5.8–9.1)

Ref

Ref

−

−

 2–3

155

5.3

(2.6–10.7)

0.7 (0.3–1.5)

0.395

−

−

  > 3

73

6.9

(2.8–16.2)

0.9 (0.4–2.4)

0.905

−

−

Use of condoms

 Generally

289

2.7

(1.5–4.9)

Ref

Ref

Ref

Ref

 Occasionally

314

6.8

(4.2–10.8)

2.5 (1.1–5.7)

0.024

2.3 (1.0–5.1)

0.050

 No

1454

8.0

(6.4–9.9)

3.0 (1.6–5.5)

0.001

1.7 (0.9–3.2)

0.105

 N/a

275

9.9

(5.7–16.5)

3.7 (1.6–8.6)

0.003

1.6 (0.6–4.7)

0.345

  1. In italics: PR is statistically significant (p < 0.05)
  2. aWe used survey weights to account for deviations of the survey sample from the sampling parameters (i.e. age, sex, region, urban/rural region, community size, citizenship and education)
  3. bIf a p-value was <0.2 in the univariable analysis, we included that variable in a stepwise forward variable selection to find a suitable multivariable model
  4. cAdjusted prevalence rates (PR) of variables which stayed in the final model (p-value ≤0.05) are reported
  5. dMen older than 65 years of age were not asked whether they visited a nursery