SOFIA®RSV: prospective laboratory evaluation and implementation of a rapid diagnostic test in a pediatric emergency ward

Table 2 Study 2. SOFIA^®RSV performance characteristics compared to PCR in infants at point-of-care

	SOFIA RSV +	SOFIA RSV-	Total	SOFIA^®RSV test performances compared to PCR (95% CI)
PCR RSV +	140	47	187	Sensitivity: 74.8% (68.0–80.9)
PCR RSV +	140	47	187	Specificity: 99.6% (97.8–100.0)
PCR RSV -	1	250	251	PPV: 99.3% (96.1–100.0)
PCR RSV -	1	250	251	NPV: 84.2% (79.5–88.1)
Total	141^a	297	438	Positive LR: 187 (26.4–1324.8)
Total	141^a	297	438	Negative LR: 0.253 (0.195–0.320)

Sensitivity, specificity, positive and negative predicted values (PPV and NPV), positive and negative likehood ratios (LR) of SOFIA^®RSV tested among infants, in the pediatric ED
CI Confidence Intervals
^a19 SOFIA^®RSV tests have been excluded since confirmation by RT-PCR has not been done for technical reasons

ISSN: 1471-2334