Evaluation of creatine kinase and liver enzymes in identification of severe dengue

Md Sani, Saiful Safuan; Han, Winn Hui; Bujang, Mohamad Adam; Ding, Hui Jen; Ng, Kiah Loon; Amir Shariffuddin, Mohd Azizuddin

doi:10.1186/s12879-017-2601-8

BMC Infectious Diseases

Table 5 Correlation coefficients and coefficients of determination for CK, AST, ALT, markers of plasma leakage and platelet count

From: Evaluation of creatine kinase and liver enzymes in identification of severe dengue

	n	Spearman r (95% CI)	p	R ²
Admission CK - Admission AST	364	0.37 (0.27 - 0.46)	<0.001	0.13^a
Admission CK - Peak AST	206	0.28 (0.15 - 0.41)	<0.001	0.07^a
Peak CK - Admission AST	104	0.29 (0.09 - 0.46)	0.003	0.06^a
Peak CK - Peak AST	92	0.22 (0.03 - 0.39)	0.020	0.06^a
Admission CK - Admission ALT	364	0.26 (0.16 - 0.35)	<0.001	0.02^b
Admission CK - Peak ALT	216	0.11 (−0.02 - 0.24)	0.110	0.01^b
Peak CK - Admission ALT	217	0.25 (0.06 - 0.42)	0.010	0.05^c
Peak CK - Peak ALT	217	0.12 (−0.08 - 0.32)	0.240	0.02^c
Admission CK - Admission Hct	364	0.24 (0.14 - 0.33)	<0.001	0.01^c
Admission CK - Nadir Platelet	363	−0.22 (−0.32 - -0.12)	<0.001	0.01^c
Admission CK - Nadir Serum Albumin	326	−0.04 (−0.15 - 0.07)	0.500	0.001^c
Peak CK - Admission Hct	104	0.03 (−0.17 - 0.22)	0.800	0.004^c
Peak CK - Nadir Platelet	104	−0.10 (−0.29 - 0.09)	0.300	0.01^c
Peak CK - Nadir Serum Albumin	104	0.06 (−0.13 - 0.25)	0.540	0.01^c
Admission AST - Admission ALT	365	0.86 (0.82 - 0.88)	<0.001	0.79^b
Admission AST - Peak ALT	217	0.68 (0.60 - 0.75)	<0.001	0.54^b
Peak AST - Admission ALT	206	0.66 (0.57 - 0.73)	<0.001	0.45^a
Peak AST - Peak ALT	189	0.92 (0.89 - 0.94)	<0.001	0.66^b
Admission Hct - Nadir Platelet	365	−0.14 (−0.24 - -0.03)	0.009	0.06^c
Admission Hct - Nadir Serum Albumin	327	0.19 (0.08 - 0.29)	0.001	0.03^c
Nadir Serum Albumin - Nadir Platelet	327	0.52 (0.43 - 0.60)	<0.001	0.14^b
Admission AST - Admission Hct	365	0.05 (−0.06 - 0.15)	0.380	0.006^c
Admission AST - Nadir Platelet	365	−0.34 (−0.43 - -0.25)	<0.001	0.04^b
Admission AST - Nadir Serum Albumin	327	−0.32 (−0.41 - -0.21)	<0.001	0.09^c
Peak AST - Admission Hct	206	−0.02 (−0.15 - 0.12)	0.800	0.01^c
Peak AST - Nadir Platelet	206	−0.38 (−0.49 - -0.26)	<0.001	0.08^c
Peak AST - Nadir Serum Albumin	200	−0.29 (−0.41 - -0.16)	<0.001	0.09^c
Admission ALT - Admission Hct	365	0.09 (−0.06 - 0.15)	0.080	0.003^c
Admission ALT - Nadir Platelet	365	−0.19 (−0.43 - -0.25)	<0.001	0.03^c
Admission ALT - Nadir Serum Albumin	327	−0.16 (−0.41 - -0.21)	0.003	0.04^c
Peak ALT - Admission Hct	217	−0.02 (−0.06 - 0.15)	0.810	0.01^c
Peak ALT - Nadir Platelet	217	−0.17 (−0.43 - -0.25)	0.020	0.01^c
Peak ALT - Nadir Serum Albumin	209	−0.13 (−0.41 - -0.21)	0.050	0.03^c

^a Power regression
^b Linear regression
^c Polynomial regression;
CK creatine kinase, AST aspartate transaminase, ALT alanine transaminase, Hct hematocrit

Back to article page

ISSN: 1471-2334

Contact us

Submission enquiries: bmcinfectiousdiseases@biomedcentral.com
General enquiries: ORSupport@springernature.com