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Table 1 Infection, immunosuppression, treatment and mortality rates (per 100 person-years) used in the model

From: Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling study

Transition rates

Women

Men

Infection rate

 15–24 years

3.0 [2.1; 4.2]

0.3 [0.1; 0.9]

 25–34 years

6.6 [4.5; 9.5]

1.9 [0.9; 4.2]

 35–59 years

1.0 [0.5; 2.0]

2.2 [1.1; 4.5]

Immunosuppression rate

 15–24 years

15.4 [7.8; 30.4]

13.8 [1.8; 105.4]

 25–34 years

6.6 [2.9; 15.1]

25.4 [11.1; 58.4]

 35–59 years

12.2 [6.0; 25.1]

13.6 [4.2; 43.8]

Treatment rate

 15–24 years

60.9 [41.5; 89.5]

10.0 [1.3; 76.1]

 25–34 years

72.6 [55.1; 95.8]

38.6 [23.9; 62.3]

 35–59 years

89.9 [68.3; 118.2]

56.2 [36.4; 86.7]

Mortality rates for individuals in compartments S, I1, and T

 15–24 years

0.12

0.16

 25–34 years

0.34

0.53

 35–44 years

0.23

0.61

 45–59 years

0.67

2.20

Mortality rates for individuals in compartment I2

 15–24 years

2.52

3.90

 25–34 years

6.58

9.85

 35–44 years

6.76

5.59

 45–59 years

8.71

8.75

  1. The infection, immunosuppression, and treatment rates were estimated using the MHIPS data whereas the mortality rates stemmed from reference [14]. Compartment S: HIV-negative individuals; compartment I1: untreated HIV-positive individuals with CD4 cell count >350 cells/mm3; compartment I2: untreated HIV-positive individuals with CD4 cell count ≤350 cells/mm3; compartment T: HIV-positive individuals on ART