Table 3 Factors associated with end of MDR-TB treatment outcomes in Brazil, multivariate analysis
From: Treatment outcomes of MDR-tuberculosis patients in Brazil: a retrospective cohort analysis
Adjusted odds of treatment success (cure/completed) vs. failure/relapse (N = 1,302) OR (95% CI) | Adjusted odds of treatment success (cure/completed) vs. failure/relapse/death (N = 1,483) OR (95% CI) | Adjusted odds of treatment success (cure/completed) vs. failure/relapse/death/lost to follow-up (N = 1,864) OR (95% CI) | |
|---|---|---|---|
HIV | |||
No | 1.7 (0.9; 3.4) | 2.7 (1.7; 4.2) | 2.3 (1.6; 3.4) |
Yes | Reference | Reference | Reference |
Regimen | |||
Standardized | 2.7 (1.8; 3.9) | 1.4 (1.1; 1.9) | 1.0 (0.8; 1.3) |
Individualized | Reference | Reference | Reference |
First DR-TB episode | |||
Yes | 8.8 (5.7; 13.5) | 5.4 (3.8; 7.7) | 2.1 (1.1; 4.1) |
No | Reference | Reference | Reference |
AFB positive | |||
No | 4.2 (2.1; 8.2) | 2.1 (1.4; 3.1) | 2.1 (1.5; 2.8) |
Yes | Reference | Reference | Reference |
Bilateral disease | – | ||
No | 1.4 (1.1.; 1.9) | 1.3 (1.1; 1.6) | |
Yes | Reference | Reference | |
Number of previous regimens | – | – | 0.4 (0.2; 0.7) |
Diabetes | – | – | |
No/Unknown | 0.7 (0.5; 0.9) | ||
Yes | Reference | ||
Macro-region | – | ||
North | 0.9 (0.3; 2.2) | 0.9 (0.5; 1.5) | – |
Northeastern | 0.2 (0.1; 0.5) | 0.4 (0.4; 0.7) | |
Centre-West | 0.4 (0.1; 1.8) | 1.0 (0.4; 2.6) | |
Southeastern | 0.4 (0.2; 0.8) | 0.7 (0.5; 1.1) | |
South | Reference | Reference | |