Between 2007 and 2011 | Between 2012 and 2015 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HCV re-tested | Person years | Rate per 100 person years (95% CI) | Univariate IRR (95% CI) | p | Multivariate IRR (95% CI) | p | HCV re-tested | Person years | Rate per 100 person years (95% CI) | Univariate IRR (95% CI) | p | Multivariate IRR (95% CI) | p | |
Age | ||||||||||||||
Every additional 5 years | 666 | 2001.5 | 33.3 (30.8–35.9) | 1.0 (0.9–1.0) | 0.07 | 1323 | 2862.2 | 46.2 (43.8–48.8) | 0.9 (0.9–1.0) | <0.01 | 1.0 (0.9–1.0)* | <0.01 | ||
Sex | ||||||||||||||
Male | 606 | 1762.8 | 34.4 (31.7–37.2) | 1.0 | 1195 | 2456.3 | 48.6 (46.0–51.5) | 1.0 | ||||||
Female | 60 | 238.8 | 25.1 (19.5–32.4) | 0.7 (0.6–1.0) | 0.02 | 128 | 405.9 | 31.5 (26.5–37.5) | 0.6 (0.5–0.8) | <0.01 | ||||
Country of birth | ||||||||||||||
Australia | 449 | 1397.4 | 32.1 (29.3–35.2) | 1.0 | 1.0 | 871 | 1903.0 | 45.8 (42.8–48.9) | 1.0 | |||||
Other | 217 | 604.1 | 35.9 (31.4–41.0) | 1.1 (1.0–1.3) | 0.18 | 1.3 (1.1–1.6) | <0.01 | 452 | 959.2 | 47.1 (43.0–51.7) | 1.0 (0.9–1.2) | 0.62 | ||
Place of residence | ||||||||||||||
Major city | 339 | 1092.4 | 31.0 (27.9–34.5) | 1.0 | 1.0 | 944 | 1726.4 | 54.7 (51.3–58.3) | 1.0 | 1.0 | ||||
Regional/remote | 316 | 878.1 | 36.0 (32.2–40.2) | 1.2 (1.0–1.4) | 0.06 | 1.3 (1.1–1.5) | <0.01 | 367 | 1085.6 | 33.8 (30.5–37.4) | 0.6 (0.5–0.7) | <0.01 | 0.7 (0.6–0.8) | <0.01 |
Unknown | 11 | 31.0 | 35.5 (19.7–64.1) | – | – | 12 | 50.2 | 23.9 (13.6–42.1) | – | – | ||||
Sexual orientation | ||||||||||||||
MSM | 528 | 1416.0 | 37.3 (34.2–40.6) | 1.7 (1.3–2.1) | 0.00 | 1.8 (1.4–2.3) | <0.01 | 996 | 1941.6 | 51.3 (48.2–54.6) | 1.3 (1.1–1.5) | <0.01 | 1.2 (1.0–1.4) | 0.03 |
Heterosexual male | 78 | 346.7 | 22.5 (18.0–28.1) | 1.0 | 1.0 | 198 | 512.7 | 38.6 (33.6–44.4) | 1.0 | 1.0 | ||||
Unknown | 60 | 238.8 | 25.1 (19.5–32.4) | – | – | 129 | 407.9 | 31.6 (26.6–37.6) | – | – | ||||
Ever performed sex work | ||||||||||||||
No | 649 | 1942.7 | 33.4 (30.9–36.1) | 1.0 | 1278 | 2783.7 | 45.9 (43.5–48.5) | 1.0 | ||||||
Yes | 17 | 58.8 | 28.9 (18.0–46.5) | 0.9 (0.5–1.4) | 0.56 | 45 | 78.5 | 57.3 (42.8–76.8) | 1.2 (0.9–1.7) | 0.14 | ||||
Ever injected drugs | ||||||||||||||
No | 507 | 1649.6 | 30.7 (28.2–33.5) | 1.0 | 1.0 | 1126 | 2513.1 | 44.8 (42.3–47.5) | 1.0 | 1.0 | ||||
Yes | 109 | 223.9 | 48.7 (40.3–58.7) | 1.6 (1.3–1.9) | <0.01 | 1.7 (1.4–2.1) | <0.01 | 148 | 256.6 | 57.7 (49.1–67.8) | 1.3 (1.1–1.5) | <0.01 | 1.3 (1.1–1.5) | 0.01 |
Unknown | 50 | 128.0 | 39.1 (29.6–51.5) | – | – | 49 | 92.5 | 52.9 (40.0–70.1) | – | – | ||||
Aboriginal or Torres Strait Islander | ||||||||||||||
No | 629 | 1915.1 | 32.8 (30.4–35.5) | 1.0 | 1.0 | 1270 | 2748.6 | 46.2 (43.7–48.8) | 1.0 | |||||
Yes | 37 | 86.4 | 42.8 (31.0–59.1) | 1.3 (0.9–1.8) | 0.12 | 1.4 (1.0–2.0) | 0.04 | 53 | 113.6 | 46.6 (35.6–61.1) | 1.0 (0.8–1.3) | 0.95 | ||
Current CD4 cell count (cells/mm3) | ||||||||||||||
≥ 500 | 164 | 596.3 | 27.5 (23.6–32.1) | 1.0 | 501 | 1107.2 | 45.2 (41.5–49.4) | 1.0 | ||||||
< 500 | 158 | 567.2 | 27.9 (23.8–32.6) | 1.0 (0.8–1.3) | 0.91 | 340 | 786.7 | 43.2 (38.9–48.1) | 1.0 (0.8–1.1) | 0.51 | ||||
Unknown | 344 | 838.1 | 41.0 (36.9–45.6) | – | 482 | 968.3 | 49.8 (45.5–54.4) | – | ||||||
Current HIV RNA | ||||||||||||||
Undetectable | 299 | 898.5 | 33.3 (29.7–37.3) | 1.0 | 758 | 1585.1 | 47.8 (44.5–51.3) | 1.0 | ||||||
Detectable | 167 | 536.3 | 31.1 (26.8–36.2) | 0.9 (0.8–1.1) | 0.49 | 243 | 465.2 | 52.2 (46.1–59.2) | 1.1 (0.9–1.3) | 0.23 | ||||
Unknown | 200 | 566.7 | 35.3 (30.7–40.5) | – | 322 | 811.9 | 39.7 (35.6–44.2) | – | ||||||
Current ART use | ||||||||||||||
Yes | 366 | 1121.3 | 32.6 (29.5–36.2) | 1.0 | 919 | 1851.9 | 49.6 (46.5–52.9) | 1.0 | ||||||
No | 100 | 313.5 | 31.9 (26.2–38.8) | 1.0 (0.8–1.2) | 0.84 | 82 | 198.5 | 41.3 (33.3–51.3) | 0.8 (0.7–1.0) | 0.11 | ||||
Unknown | 200 | 566.7 | 35.3 (30.7–40.5) | – | 322 | 811.9 | 39.7 (35.6–44.2) | – | ||||||
Current calendar year~ | ||||||||||||||
2007 / 2012 | 74 | 236.7 | 31.3 (24.9–39.3) | 1.0 | 1.0 | 279 | 760.9 | 36.7 (32.6–41.2) | 1.0 | 1.0 | ||||
2008 / 2013 | 167 | 424.3 | 39.4 (33.8–45.8) | 1.3 (1.0–1.7) | 0.10 | 1.3 (1.0–1.7) | 0.07 | 361 | 819.4 | 44.1 (39.7–48.8) | 1.2 (1.0–1.4) | 0.02 | 1.2 (1.0–1.4) | 0.02 |
2009 / 2014 | 155 | 487.2 | 31.8 (27.2–37.2) | 1.0 (0.8–1.3) | 0.90 | 1.1 (0.8–1.4) | 0.66 | 414 | 808.1 | 51.2 (46.5–56.4) | 1.4 (1.2–1.6) | <0.01 | 1.4 (1.2–1.6) | <0.01 |
2010 / 2015 | 158 | 487.3 | 32.4 (27.7–37.9) | 1.0 (0.8–1.4) | 0.80 | 1.1 (0.8–1.4) | 0.52 | 269 | 473.8 | 56.8 (50.4–64.0) | 1.5 (1.3–1.8) | <0.01 | 1.5 (1.3–1.8) | <0.01 |
2011 / - | 112 | 366.0 | 30.6 (25.4–36.8) | 1.0 (0.7–1.3) | 0.89 | 1.1 (0.8–1.4) | 0.74 | – | – | – | – | – |