Skip to main content

Table 2 Comparison of clinical characteristics between sporadic and familial cases of isolated congenital asplenia

From: Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review

 

Sporadic n = 32

Familial n = 41

P value

Age at diagnosis, years

2.1 (0.8–34.2)

1.0 (0.6–3.0)

0.04

Male sex

11a (44)

25(61)

0.18

Clinical events

 Sepsis and/ or meningitis

25(78)

24 (58)

0.08

 Others

6 (19)

2 (5)

0.06

 Asymptomatic

1 (3)

15 (37)

0.001

Pathogens

 S. pneumoniae

16b (62)

14c (56)

0.69

 H. influenzae

5b (19)

3c (12)

0.48

 Others

3b (12)

0c (0)

0.08

Howell- Jolly bodies

18 (56)

17 (41)

0.21

Outcome

 Death

12 (38)

16 (39)

0.68

  1. Values are presented as median (interquartile range) or number (percentage). P < 0.05 is considered to be significant. adata from 25 patients were available. bdata from 26 patients were available. cdata from 25 patients were available