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Table 2 Demographics and clinical characteristics of TIV-vaccinated vs unvaccinated patients ≥16 years (all adults group)

From: Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case-control study in adults in Canada

 

Not vaccinated

N = 587

TIV

N = 776

p-value

Age, years

 Mean (SD)

61.35 (19.76)

73.68 (14.94)

<0.001

 Median (range)

64 (18–98)

76 (18–104)

 

Age subgroups, n (%)

 16–49 years

161 (27.4)

53 (6.8)

<0.001

 50–64

143 (24.4)

122 (15.7)

 

 65–75 years

112 (19.1)

195 (25.1)

 

 > 75 years

171 (29.1)

406 (52.3)

 

Female, n (%)

337 (57.4)

420 (54.1)

0.248

BMI, kg/m2

 Mean (SD)

26.72 (6.66)

26.68 (7.16)

0.915

 Median (range)

25.49 (11.38–60.35)

25.67 (6.64–63.77)

 

Obese (BMI ≥30 kg/m2), n (%)

136 (23.2)

196 (25.3)

0.480

 ≥ 1 co-morbidity, n (%)

 Cardiac disease

195 (33.2)

568 (73.2)

<0.001

 Vascular disease

427 (55.0)

241 (41.1)

<0.001

 Pulmonary disease

297 (50.6)

401 (51.7)

<0.001

Smoking, n (%)

 Current

127 (21.6)

105 (13.5)

<0.001

 Past

162 (27.6)

315 (40.6)

<0.001

Admitted from a LTCF

15 (2.6)

70 (9.0)

<0.001

≤4 prescribed medications before admission

287 (48.9)

169 (21.8)

<0.001

  1. N number of patients, TIV trivalent influenza vaccine, SD standard deviation, BMI body mass index, LTCF long-term care facility
  2. Missing data: BMI: 29 not vaccinated (4.9%), 26 TIV-vaccinated (3.4%); Obesity: 29 not vaccinated (4.9%), 26 TIV-vaccinated (3.4%); Current smoking: 1 not vaccinated (0.2%), 11 TIV-vaccinated (1.4%); Past smoking: 131 not vaccinated (22.3%), 130 TIV-vaccinated (16.7%); Admitted from a LTCF: 0 not vaccinated (0.0%), 1 TIV-vaccinated (0.1%); ≤4 prescribed medications before admission: 10 not vaccinated (1.7%), 7 TIV-vaccinated (0.9%)