Table 3 Risk factors for neonatal bacterial eye infection
Characteristic | Both trial arms | Placebo arm only | ||||||
|---|---|---|---|---|---|---|---|---|
N | n (%) | OR (95%CI) | p-value | N | n (%) | OR (95%CI) | p-value | |
>18 h membrane rupture to birth | ||||||||
No | 384 | 2.3 | 1 | 205 | 2.9 | 1 | ||
Yes | 459 | 2.6 | 1.12 (0.47,2.68) | 0.829 | 219 | 4.6 | 1.59 (0.57,4.45) | 0.45 |
Gender | ||||||||
Female | 405 | 1.7 | 1 | 198 | 2.5 | 1 | ||
Male | 438 | 3.2 | 1.88 (0.75,4.70) | 0.191 | 226 | 4.9 | 1.97 (0.67,5.79) | 0.307 |
Apgar score | ||||||||
0 | 12 | 0.0 | NA | 6 | 0.0 | NA | ||
1–6 | 13 | 0.0 | NA | 5 | 0.0 | NA | ||
7–10 | 810 | 2.6 | NA | 1 | 408 | 3.9 | NA | 1 |
Low birth-weight (<2.5 kg) | ||||||||
No | 786 | 2.5 | 1 | 392 | 3.8 | 1 | ||
Yes | 55 | 1.8 | 0.71 (0.09,5.39) | 1 | 30 | 3.3 | 0.87 (0.11,6.79) | 1 |
Bacteria in the vaginal swab prior to intervention | ||||||||
No | 615 | 2.3 | 1 | 302 | 3.3 | 1 | ||
Yes | 228 | 3.1 | 1.36 (0.54,3.41) | 0.468 | 122 | 4.9 | 1.51 (0.54,4.25) | 0.412 |
Season | ||||||||
Dry | 557 | 2.0 | 1 | 280 | 2.9 | 1 | ||
Wet | 286 | 3.5 | 1.80 (0.75,4.29) | 0.242 | 144 | 5.6 | 2.00 (0.73,5.44) | 0.184 |
Tetracycline at birth | ||||||||
No | 99 | 3.0 | 1 | 47 | 6.4 | 1 | ||
Yes | 743 | 2.4 | 0.79 (0.23,2.75) | 0.728 | 377 | 3.4 | 0.52 (0.14,1.91) | 0.404 |
Mothers’ years of schooling | ||||||||
< 1 year | 424 | 2.6 | 1 | 210 | 3.8 | 1 | ||
1+ years | 398 | 2.5 | 0.97 (0.41,2.30) | 1 | 203 | 3.9 | 1.04 (0.38,2.81) | 1 |
Ethnicity | ||||||||
Madinka | 352 | 2.3 | 1 | 189 | 3.7 | 1 | 0.691 | |
Wollof | 94 | 1.1 | 0.46 (0.06,3.74) | 47 | 2.1 | 0.57 (0.07,4.71) | 0.691 | |
Jola | 127 | 5.5 | 2.51 (0.89,7.06) | 59 | 6.8 | 1.89 (0.53,6.70) | 0.691 | |
Fula | 144 | 2.8 | 1.23 (0.36,4.15) | 66 | 4.5 | 1.24 (0.31,4.93) | 0.691 | |
Other | 106 | 0.9 | 0.41 (0.05,3.31) | 0.23 | 56 | 1.8 | 0.47(0.06,3.93) | 0.691 |