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Table 1 Sensitivities and specificities of four individual antigens and the multiple-antigen combination set with serum from LTBI individuals and healthy controls

From: ORFeome-based identification of biomarkers for serodiagnosis of Mycobacterium tuberculosis latent infection

Rv.

Latent TB (N = 62)

Sensitivity (%, 95% CI)

Healthy controls (N = 32)

Specificity (%, 95% CI)

Specific

Positive

Nonspecific

Positive

Negative

Positive

Negative

Rv1146

2

20

40

35.5 (24.0–48.7)

1

31

96.9 (82.0–99.8)

Rv1977

6

21

35

43.6 (31.2–56.7)

1

31

96.9 (82.0–99.8)

Rv3090

4

16

42

32.3 (21.3–45.5)

1

31

96.9 (82.0–99.8)

Rv3206c

3

19

40

35.5 (24.0–48.7)

2

30

93.8 (77.8–98.9)

Multiple

41

 

21

66.1 (52.9–77.4)

4

28

87.5 (70.1–95.1)

  1. Abbreviation: CI confidence intervals. Specific Positive: serum samples which recognized only one of four antigens; Nonspecific Positive: serum samples which reacted with various antigens