Fig. 4

Dynamics of NLRP3, caspase-1, and IL-1β mRNA expression in organs of rabbits infected with T. pallidum. a-e Dynamics of NLRP3 mRNA expression in the kidney (a), liver (b), lung (c), spleen (d) and testis (e). f-j Dynamics of caspase-1 mRNA expression in the kidney (f), liver (g), lung (h), spleen (i) and testis (j). k-o Dynamics of IL-1β mRNA expression in the kidney (k), liver (l), lung (m), spleen (n) and testis (o). Values represent the mean ± SD of triplicate experiments. A one-way analysis of variance was employed to examine the differences in groups, and Dunnett’s post-comparison test was used to conduct multiple comparisons. * P < 0.05, the BPG treatment subgroup or no BPG treatment subgroup vs. the blank group