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Table 1 Baseline characteristics of immunocompromised patients with RSV infection

From: Burden of severe RSV disease among immunocompromised children and adults: a 10 year retrospective study

Variable; number (%) unless indicated otherwise

CHILDREN N = 64

ADULTS N = 175

TOTAL N = 239

Variable; number (%) unless indicated otherwise

INPATIENTS

OUTPATIENTS

INPATIENTS

OUTPATIENTS

INPATIENTS

OUTPATIENTS

N = 48

N = 16

N = 107

N = 68

N = 155

N = 84

< 2 years

11 (23)

2 (12.5)

    

2–5 years

13 (27.1)

7 (43.75)

    

5–18 years

24 (50)

7 (43.75)

    

Age (years) median (IQR)

4.9 (2.7–7.4)

47 (.3.7–8.8)

60.5 (48–70.6)

50.8 (37.3–59.4)

  

Male

26 (54.2)

9 (56.3)

53 (49.5)

34 (20)

79 (51)

43 (51,2)

HSCT

2 (4.2)

6 (37.5)

24 (22.4)

35 (51.5)

26 (16.8)

41 (48.8)

Autologous

0

0

9 (8.4)

1 (1.5)

9 (5.8)

1(1.2)

Allogeneic

0

8(100)

15 (14)

34 (50)

12(7,7)

45(53,6)

Matched

0

3 (18.8)

5 (4.7)

19(28)

5(3,2)

22(26,2)

Mismatched

0

0

1 (1)

0

1(0,6)

0

Unrelated

2 (4.2)

1 (6.3)

9 (8.4)

15(22,1)

11(7,1)

16(19)

SOT

3(6.3)

2 (12.5)

32 (30)

26(38,2)

35(22,6)

28(33,3)

Leukaemia /lymphoma

23 (47.9)

6 (37.5)

18 (16.8)

3(4,4)

41(26,5)

9(10,7)

Solid tumor

9 (18.8)

2 (12.5)

15 (14)

1(1,5)

24(15,5)

3(3,6)

Chronic immuno-suppression

6 (12.5)

0

18 (16.8)

2 (3.0)

24(15,5)

2(2,4)

PID

5 (10.4)

0

0

1(1)

5(3,2)

1(1,2)

GVHD among allogeneic HSCT recipients

1 (2.1)

4 (25)

9 (8.4)

21 (30.9)

10(6,5)

25(29,8)

Bacterial co-infection

8 (16.7)

1(6.3)

25 (23.4)

2 (3)

33(21,3)

3(3,6)

Viral co-infection

12 (25)

6 (37.5)

22 (20.6)

12 (17.7)

34(21,9)

18(21,4)

ANC, median, (IQR)

1.1 (0.5–3.1)

1.7 (1.6–4.2)

4.6 (1.4–8.1)

3.5 (2.6–5.3)

3.4 (0.9–6.7)

3.3 (2.3–5.3)

ALC, median (IQR)

0.8 (0.2–2.1)

1.6 (0.7–1.9)

0.7 (0.1–1.1)

1.1 (0.6–1.9)

0,7(0,2–1,4)

1.1 (0.6–1.9)

Oral ribavirin treatment

1 (2.1)

1 (6.3)

24 (22.4)

12 (17,6)

25 (16.1)

13(15,5)

Palivizumab treatment

2 (4.2)

0

7 (6.5)

1 (1.5)

9 (5,8)

1(1,2)

  1. Absolute neutrophil counts (ANC), Absolute lymphocyte counts (ALC), Graft vs. host disease (GVHD), Hematopoietic stem cell transplant (HSCT), Interquartile range (IQR), Primary Immunodeficiency Disease (PID), Solid Organ Transplant (SOT)
  2. Number of missing values: Children outpatients: ANC N = 1, ANC =1; adult inpatients ANC N = 5, ALC N = 5; adult outpatients ANC N = 13, ALC N = 13
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BMC Infectious Diseases

ISSN: 1471-2334

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