Skip to main content

Table 1 Analyses of risk factors for the incidence of liver failure in all patients (n = 84)

From: Co-infection with hepatitis B virus among tuberculosis patients is associated with poor outcomes during anti-tuberculosis treatment

Factors

Univariate analysis

Multivariate analysis

OR

95%CI

P-value

OR

95%CI

P-value

Age > 50

1.913

0.79, 4.64

0.151

1.603

1.930

0.55, 4.67

0.75, 4.92

0.387

0.169

Male

1.774

0.61, 5.18

0.294

0.581

0.848

0.16, 2.16

0.20, 2.97

0.417

0.796

Alcohol intake > 40 g/d

1.081

0.28, 4.16

0.909

–

–

–

INH + RFP

0.469

0.16, 1.36

0.165

0.775

0.538

0.21, 2.86

0.18, 1.64

0.702

0.275

Latency < 1 month

0.667

0.21, 2.11

0.490

–

–

–

Hepatocellular DILI

0.689

0.27, 1.76

0.435

–

–

–

Cirrhosis

13.347

4.05, 43.98

0.000

11.484

3.16, 41.73

0.000

HBsAg-positive

3.284

1.26, 8.59

0.015

2.658

3.232

1.19, 5.58

1.08, 9.64

0.041

0.035

  1. In addition to male gender, variables with P < 0.200 in the univariate analysis were included in the multivariate analysis. Adjusted statistical data were shown in italic font if the variable of cirrhosis was discarded due to its correlation with chronic HBV infection
  2. Abbreviations: INH isoniazid, RFP rifampin, DILI drug-induced liver injury, HBsAg hepatitis B virus surface antigen
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us