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Table 2 Analyses of risk factors for the incidence of liver failure in the TB-HBV group (n = 58)

From: Co-infection with hepatitis B virus among tuberculosis patients is associated with poor outcomes during anti-tuberculosis treatment

Factors

Univariate analysis

Multivariate analysis

OR

95%CI

P-value

OR

95%CI

P-value

Age > 50

1.306

0.43, 3.95

0.636

1.024

0.26, 3.99

0.973

Male

3.469

0.53, 22.80

0.195

1.199

0.14, 10.09

0.868

Alcohol intake > 40 g/d

0.429

0.06, 1.57

0.272

–

–

–

INH + RFP

0.533

0.15, 1.93

0.339

0.586

0.13, 2.61

0.483

Latency < 1 month

0.429

0.09, 1.94

0.272

–

–

–

Hepatocellular DILI

0.638

0.19, 2.15

0.467

–

–

–

Cirrhosis

9.545

7.7, 170.83

0.001

9.648

2.39, 38.87

0.001

HBV DNA > 20,000 IU/ml

1.045

0.34, 3.18

0.938

0.607

0.16, 2.33

0.466

  1. Abbreviations: TB tuberculosis, INH isoniazid, RFP rifampin, DILI drug-induced liver injury, HBV hepatitis B virus
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BMC Infectious Diseases

ISSN: 1471-2334

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