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Table 1 Demographics of the study groups and biochemical parameters in TB-DM TB and HC

From: Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment

Study Demographics

TB-DM

TB

HC

p Value

No. of subjects recruited

64

24

24

–No significance

Gender (Male / Female)

44/20

17/7

14/10

–No significance

Median Age (Range)

52 (31–70)

43 (30–67)

35(27–62)

–No significance

Median Height, cm

159 (129–176)

164 (121–181)

162 (125–190)

–No significance

Median Weight, kg

49 (31–64)

44 (30–90)

55 (45–90)

–No significance

Body mass index kg/m2

19.3 (13.2–32.6)

17.2 (12.2–21.2)

22.3 (18.2–24.7)

–No significance

Smear Grade: 0/1+/2+/3+

0/22/24/18

0/9/9/6

NA

–No significance

Fasting Blood Glucose, mg/dL

158 (109–427)

93 (73–103)

88 (75–105)

p < 0.0001

Post Prandial Glucose, mg/dL

220 (183–448)

112 (80–129)

110 (78–120)

p < 0.0001

Glycated hemoglobin level, %

10.3 (7.3–15.6)

5.6 (5.0–5.8)

5.5 (5.0–5.7)

p < 0.0001

  1. The values represent the geometric mean (and the 95% confidence intervals) except for age where the median (and the range) are depicted. P values were calculated using the Kruskal-Wallis test with Dunn’s post-hoc for multiple comparisons
  2. P values captured in bold are statistically significant