Good concordance of HPV detection between cervico-vaginal self-samples and general practitioner-collected samples using the Cobas 4800 HPV DNA test

Table 1 Concordance and agreement for HPV detection (any type) between self-samples and GP-collected samples

	GP-collected samples						κ^b (95% CI)	Agreement (%) (95% CI)	Sensitivity (%) (95% CI)	Specificity (%) (95% CI)
	HPV any positive^a		HPV negative		Total
	n	%	n	%	n	%
Self-samples
HPV any positive^a	38	17.8	14	6.6	52	24.4	0.70 (0.58–0.81)	89.2 (84.2–93.0)	80.9 (66.7–90.9)	91.6 (86.3–95.3)
HPV negative	9	4.2	152	71.4	161	75.6
Total	47	22.1	166	77.9	213	100.0

^aHPV any positive: HPV16 and/or HPV18 and/or HPV31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. % = Row percentage
^bCohen’s Kappa. “Poor” (κ ≤ 0.20), “Fair” (0.21 ≤ κ ≤ 0.40), “Moderate” (0.41 ≤ κ ≤ 0.60), “Good” (0.61 ≤ κ ≤ 0.80), or “Very good” (κ ≥ 0.81) (18)

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