Table 1 Baseline characteristics by year of HIV-positive patients on ART (Section A) and not on ART (Section B) at the start of TB treatment
From: HIV and TB co-infection in the ART era: CD4 count distributions and TB case fatality in Cape Town
Start year | 2009 | 2010 | 2011 | 2012 | 2013 | Total |
|---|---|---|---|---|---|---|
All HIV-positive patients | 12,372 | 12,749 | 12,490 | 11,811 | 11,060 | 60,482 |
Section A. | ||||||
HIV-positive patients on ART n (%) | 1221 (9.9) | 1617 (12.7) | 2235 (17.9) | 3322 (28.1) | 3313 (30.0) | 11,708 (19.4) |
Age, years, median [IQR] | 35 [29–41] | 34 [29–40] | 36 [30–41] | 35 [30–42] | 36 [30–42] | 35 [30–41] |
Gender | ||||||
Female n (%) | 746 (61.1) | 980 (60.6) | 1323 (59.2) | 1870 (56.3) | 1880 (56.7) | 6799 (58.1) |
Classification | ||||||
New TB n (%) | 678 (55.5) | 888 (54.9) | 1249 (55.9) | 1890 (56.9) | 1953 (58.9) | 6658 (56.9) |
Retreatment TB n (%) | 543 (44.5) | 729 (45.1) | 986 (44.1) | 1432 (43.1) | 1360 (41.1) | 5050 (43.1) |
Category | ||||||
PTB n (%) | 885 (72.5) | 1184 (73.2) | 1725 (77.2) | 2668 (80.3) | 2758 (83.2) | 9220 (78.7) |
EPTB n (%) | 336 (27.5) | 433 (26.8) | 510 (22.8) | 654 (19.7) | 555 (16.8) | 2488 (21.3) |
Median CD4 | 150 [74–242] | 153 [75–254] | 169 [80–290] | 178 [80–315] | 202 [91–348] | 175 [81–305] |
Section B. | ||||||
HIV-positive patients not on ART n (%) | 11,142 (90.1) | 11,130 (87.3) | 10,255 (82.1) | 8,481 (71.8) | 7,741 (70.0) | 48,749 (80.6) |
Age, years, median [IQR] | 34 [28-40] | 34 [28-40] | 34 [29-41] | 35 [29-41] | 35 [29-41] | 34 [29-41] |
Gender | ||||||
Female n (%) | 5,839 (52.4) | 5,973 (53.7) | 5,367 (52.3) | 4,313 (50.9) | 3,892 (50.3) | 25,384 (52.1) |
Classification | ||||||
New TB n (%) | 7,957 (71.4) | 7,930 (71.2) | 7,259 (70.8) | 6,035 (71.2) | 5,830 (75.3) | 35,011 (71.8) |
Retreatment TB n (%) | 3,185 (28.6) | 3,200 (28.8) | 2,996 (29.2) | 2,446 (28.8) | 1,911 (24.7) | 13,738 (28.2) |
Category | ||||||
PTB n (%) | 8,860 (79.5) | 8,808 (79.1) | 8,186 (79.8) | 6,964 (82.1) | 6,370 (82.3) | 39,188 (80.4) |
EPTB n (%) | 2,282 (20.5) | 2,322 (20.9) | 2,069 (20.2) | 1,517 (17.9) | 1,371 (17.7) | 9,561 (19.6) |
Median CD4 count [IQR] | 152 [69-281] | 160 [72-289] | 174 [78-308] | 176 [74-319] | 162 [67-313] | 164 [72-300] |