Table 1 Susceptibility to the antimicrobial agents, basic characterization and drug resistance gene of CNSE
Isolate NO. | MIC(ug/mL) | bla genotype | MHT/mCIM | strain | Culture type | History of antibiotic use | Invasive procedure | outcome | MLST | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMP | AMS | TZP | CZO | CAZ | CRO | FEP | ATM | IMP | AMK | GEN | TOB | CIP | LEV | |||||||||
CNSE01 CNSE02 CNSE15 | R | R | R | R | R | R | R | R | R | S | R | R | R | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |
CNSE03 CNSE09 CNSE12 CNSE44 CNSE48 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Died | ST76 |
CNSE04 CNSE05 CNSE07 CNSE14 CNSE16 CNSE29 CNSE30 CNSE31 CNSE32 CNSE34 CNSE35 CNSE54 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |
CNSE06 | R | R | R | R | R | R | R | R | R | S | S | S | S | S | KPC-2, SHV | +/+ | KP | Sputum | YES | YES | Died | ST323 |
CNSE08 CNSE11 | R | R | R | R | R | R | R | R | R | S | R | R | R | R | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |
CNSE10 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | NO | NO | Survived | ST76 |
CNSE17 | R | R | R | R | R | R | R | R | R | S | R | R | S | S | KPC-2, SHV, CTX-M-15 | +/− | KP | Sputum | YES | YES | Died | ST76 |
CNSE18 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Died | ST76 |
CNSE19 | R | R | R | R | R | R | R | R | R | S | S | I | R | R | KPC-2, NDM-5, CTX-M-14, TEM | −/+ | EC | Blood | YES | YES | Survived | ND |
CNSE20 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, NDM-5, SHV, CTX-M-177, TEM | +/+ | KP | Sputum | YES | YES | Died | ST76 |
CNSE22 | R | R | R | R | R | R | R | R | R | S | R | I | S | S | IMP-4, SHV, TEM | +/+ | KP | Sputum | YES | YES | Died | ST896 |
CNSE23 | R | R | R | R | R | R | R | R | R | S | R | R | R | R | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Blood | YES | YES | NR | ST76 |
CNSE24 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Blood | YES | YES | Survived | ST76 |
CNSE25 | R | R | R | R | R | R | R | R | R | S | R | R | R | R | NDM-1, TEM, CTX-M-15 | +/+ | EC | Sputum | YES | YES | Survived | ND |
CNSE26 | R | R | R | R | R | R | R | S | R | S | S | S | S | S | IMP-4 | +/+ | KO | Sputum | YES | NO | Survived | ND |
CNSE27 | R | R | R | R | R | R | R | R | R | R | R | R | R | R | NDM-7, TEM, CTX-M-15 | −/+ | EC | Urine | YES | YES | Survived | ND |
CNSE28 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Blood | YES | YES | Died | ST76 |
CNSE36 | R | R | R | R | R | R | R | R | R | S | R | R | R | I | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Secretion | YES | YES | Survived | ST76 |
CNSE37 | R | R | R | R | R | R | R | R | I | S | R | I | S | S | IMP-4, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Died | ST2964 |
CNSE38 | R | R | R | R | R | R | R | R | R | S | R | R | S | S | NDM-1, SHV, CTX-M-15 | −/+ | ECL | Secretion | YES | YES | Survived | ND |
CNSE39 | R | R | R | R | R | R | R | R | R | S | S | S | S | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |
CNSE40 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KO | Sputum | YES | YES | Survived | ND |
CNSE41 | R | R | R | R | R | R | R | R | S | S | R | R | R | S | – | −/+ | SM | Secretion | NR | NR | NR | ND |
CNSE42 | R | R | R | R | R | R | R | R | I | R | R | R | S | S | IMP-4, TEM | +/+ | ECL | Blood | YES | YES | Died | ND |
CNSE43 | R | R | R | R | R | R | R | R | R | S | R | R | R | R | KPC-2, SHV, TEM, DHA | +/+ | ECL | Sputum | YES | YES | Died | ND |
CNSE45 | R | R | R | R | R | R | R | R | R | R | R | R | R | R | KPC-2, TEM | +/+ | CF | pus | YES | YES | Survived | ND |
CNSE46 | R | R | R | R | R | R | R | R | R | S | R | I | R | R | NDM-1 IMP-4, SHV, TEM, CTX-M-15 | +/+ | ECL | Urine | YES | YES | Survived | ND |
CNSE47 | R | R | R | R | R | R | R | R | R | S | S | S | R | R | KPC-2, SHV | −/+ | KP | Blood | YES | YES | Survived | ST11 |
CNSE49 | R | R | R | R | R | R | R | R | R | S | R | R | R | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Blood | YES | YES | Survived | ST76 |
CNSE50 | R | R | R | R | R | R | R | R | R | S | R | R | R | R | KPC-2, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |
CNSE51 | R | R | R | R | R | R | R | R | R | S | S | S | R | R | KPC-2, IMP-4, TEM, DHA | +/+ | ECL | pus | YES | YES | Survived | ND |
CNSE52 | R | R | R | R | R | R | R | R | R | S | R | R | I | S | KPC-2, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |
CNSE53 | R | R | R | R | R | R | R | S | R | R | R | R | R | R | NDM-5, SHV | +/+ | EC | Blood | YES | YES | Died | ND |
CNSE55 | R | R | R | R | R | R | R | R | R | S | R | R | R | S | KPC-2, SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | NR | ST76 |
CNSE56 | R | R | R | R | R | R | R | R | R | S | R | R | R | S | SHV, TEM, CTX-M-15 | +/+ | KP | Sputum | YES | YES | Survived | ST76 |