Table 1 Patient baseline characteristics
Baseline Characteristics | Conventional period n = 302 (%) | MALDI-TOF period n = 254 (%) | P Value† |
|---|---|---|---|
Age (years), mean ± SD | 63.5 ± 12.3 | 61.6 ± 13.9 | 0.088 |
Female | 114 (37.7) | 136 (53.5) | < 0.001 |
Underlying disease | |||
Solid tumor | 169 (56.0) | 133 (52.4) | 0.396 |
Hematologic malignancy | 27 (8.9) | 20 (7.9) | 0.653 |
Cardiovascular disease | 54 (17.9) | 54 (21.3) | 0.316 |
Cerebrovascular disease | 30 (9.9) | 35 (13.8) | 0.160 |
Chronic lung disease | 7 (2.3) | 9 (3.5) | 0.389 |
Chronic liver disease | 44 (14.6) | 26 (10.2) | 0.125 |
Chronic kidney disease | 42 (13.9) | 34 (13.4) | 0.858 |
Transplantation | 16 (5.3) | 11 (4.3) | 0.597 |
Charlson score, median (IQR) | 6 (2–7) | 6 (2–7) | 0.505 |
Clinical conditions | |||
Prior Chemotherapy within 30 days | 81 (26.8) | 63 (24.8) | 0.588 |
Neutropenia (ANC < 500 cells/μL) | 26 (8.6) | 19 (7.5) | 0.627 |
ICU stay | 51 (16.9) | 47 (18.5) | 0.618 |
SOFA score, mean ± SD | 3.7 ± 3.6 | 4.2 ± 3.6 | 0.110 |
Acquisition of BSI | |||
Community acquired | 190 (62.9) | 165 (65.0) | 0.617 |
Hospital acquired | 112 (37.1) | 89 (35.0) | 0.617 |
Source of BSI | |||
Urinary tract | 61 (20.2) | 57 (22.4) | 0.519 |
Respiratory tract | 38 (12.6) | 23 (9.1) | 0.185 |
Biliary tract | 73 (24.2) | 63 (24.8) | 0.863 |
Abdomen except biliary tract | 29 (9.6) | 23 (9.1) | 0.825 |
Central venous catheter | 32 (10.6) | 27 (10.6) | 0.990 |
Foreign device | 5 (1.7) | 2 (0.8) | 0.462 |
SSTI/BJI | 20 (6.6) | 10 (3.9) | 0.163 |
Infective endocarditis | 6 (2.0) | 4 (1.6) | 0.761 |
Primary Unknown | 38 (12.6) | 45 (17.7) | 0.091 |