Table 2 Factors associated with detection of ceftriaxone-resistant Enterobacteriaceae colonization among 561 patients without ceftriaxone-resistant Enterobacteriaceae colonization at enrollment
Risk Factor, n (%) | Ceftriaxone-resistant Enterobacteriaceae colonization, n (%) | Unadjusted OR (95% CI) | p-value | Adjusted ORa (95% CI) | p-value | |
|---|---|---|---|---|---|---|
No acquisition, N = 512 | Acquisition, N = 49 | |||||
Age in years | ||||||
  < 5 | 163 (32) | 21 (43) | 4.7 (1.3–29.9) | 0.04 | 4.4 (1.2–28.7) | 0.06 |
 5–11 | 88 (17) | 5 (10) | 2.1 (0.4–14.8) | 0.39 | 2.0 (0.4–14.6) | 0.41 |
 12–23 | 73 (14) | 2 (4) | Ref | Ref | Ref | Ref |
 24–59 | 154 (30) | 15 (31) | 3.6 (1–22.9) | 0.1 | 3.8 (1–24.9) | 0.08 |
  ≥ 60 | 34 (7) | 6 (12) | 6.4 (1.4–45.5) | 0.03 | 7.0 (1.5–50.1) | 0.02 |
 Male sex | 307 (60) | 33 (67) | 1.4 (0.7–2.8) | 0.36 | 1.5 (0.8–2.9) | 0.23 |
 Income < 5000 INR / month | 183 (36) | 23 (47) | 1.6 (0.0–8-3) | 0.12 |  |  |
 Farmer or laborer | 203 (40) | 24 (49) | 1.5 (0.8–2.7) | 0.22 |  |  |
 HIVb | 56 (22) | 6 (27) | 1.3 (0.4–3.7) | 0.6 |  |  |
 ICU | 102 (20) | 17 (35) | 2.1 (1.1–4.1) | 0.03 | 1.6 (0.8–3.4) | 0.18 |
Pre-hospital antibiotic use | ||||||
 Within the past week | 99 (19) | 13 (27) | 1.5 (0.7–3.0) | 0.26 |  |  |
 Within the past month | 121 (24) | 14 (29) | 1.3 (0.6–2.6) | 0.48 |  |  |
Initial inpatient antibiotic Rx | ||||||
 Any antibiotic | 432 (84) | 45 (92) | 2.1 (0.7–8.2) | 0.21 |  |  |
 Multiple antibiotics | 240 (47) | 30 (61) | 1.8 (0.9–3.5) | 0.07 |  |  |
 3rd-gen cephalosporin | 234 (46) | 35 (71) | 3.0 (1.5–6.1) | < .01 | 2.9 (1.5–5.8) | < 0.01 |
 Fluoroquinolone | 19 (4) | 1 (2) | 0.5 (0.0–3.6) | 1 |  |  |
 Macrolide | 96 (19) | 13 (27) | 1.6 (0.7–3.2) | 0.19 |  |  |
 Aminoglycoside | 53 (10) | 8 (16) | 1.7 (0.6–3.9) | 0.23 |  |  |