Skip to main content

Table 2 Clinical success rate in 43 cryptococcal meningitis patients treated with high dose fluconazole for salvage therapy

From: High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis

Time point

Total

(N = 43)

H-Flu ±5FC

(N = 32)

H-Flu + AmB ± 5FC

(N = 11)

P-value

2-week of Salvage Therapy

31 (72.1)

20 (62.5)

11 (100)

0.019

End of Salvage Therapy

36 (83.7)

27 (84.4)

9 (81.8)

>  0.999

End of Antifungal Therapy

37 (86.0)

27 (84.4)

10 (90.9)

>  0.999

  1. H-Flu high dose fluconazole (800 mg/day); AmB Amphotericin B; 5FC flucytosine