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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: Early sofosbuvir-ledipasvir treatment for acute HCV infection induced severe immune thrombocytopenia – a case report

Fig. 1

Platelet and HCV viral load. Acute genotype 1a HCV reinfection was diagnosed on August 2017 on a systematic survey, with 11 xULN ALT and 5.91 log IU/mL HCV RNA. Platelets were found at 5 G/L for the unit admission on August 30, 2017. First course of IVIG was administrated on August 31, at the dose of 1 g/kg on day 1 and day 3, with clinical benefit but no effect on the platelet count. Second IVIG course was administrated on September 05 in association with methylprednisolone 1 mg/kg daily. Sofosbuvir-ledipasvir was started on September 11, allowing a sustained recovery of the platelet count with a quick viral load control (basal blue line represents an undetectable HCV viral load, inferior to 12 IU/mL). IVIG: intravenous immunoglobulin, MP: methylprednisolone, SOF-LDV: sofusbuvir-ledispavir, ALT: Alanine transaminase, HCV: Hepatitis C virus

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