Table 1 Characteristics of adults with HIV stratified by tuberculosis status
All Individuals N=654 | Active TB N=96 | Subclinical TB N=28 | No Microbiologic TB/ATT1 N=40 | No Microbiologic TB/No ATT N=490 | P Value | |
|---|---|---|---|---|---|---|
Demographics | ||||||
Mean age, years (SD) | 34 (9) | 35 (9) | 33 (9) | 36 (11) | 34 (10) | 0.55 2 |
Men | 348 (53%) | 65 (68%) | 14 (50%) | 21 (53%) | 248 (51%) | 0.02 |
Education: high school or higher | 249 (38%) | 34 (36%) | 8 (29%) | 12 (30%) | 195 (40%) | 0.39 |
Marital status | ||||||
Never married | 542 (83%) | 83 (87%) | 22 (79%) | 32 (80%) | 405 (83%) | 0.53 |
Currently married | 89 (14%) | 9 (9%) | 6 (21%) | 7 (18%) | 67 (14%) | 0.29 |
Clinical | ||||||
Current tobacco | 160 (25%) | 19 (20%) | 7 (25%) | 8 (20%) | 126 (26%) | 0.61 |
Prior TB treatment | 53 (8%) | 8 (8%) | 0 | 3 (8%) | 42 (9%) | 0.34 |
TB-related symptoms | ||||||
None | 243 (37%) | 0 | 28 (100%) | 7 (18%) | 208 (42%) | -- |
Any 1 symptom | 139 (21%) | 23 (24%) | 0 | 11 (28%) | 105 (21%) | -- |
Any 2 symptoms | 116 (18%) | 73 (76%) | 0 | 22 (55%) | 177 (36%) | -- |
Any 3 symptoms | 85 (13%) | 53 (55%) | 0 | 14 (35%) | 89 (18%) | -- |
All 4 symptoms | 71 (11%) | 23 (24%) | 0 | 6 (15%) | 42 (9%) | -- |
Median CD4 cell count (IQR), cells/mm3 | 206 (81 – 349) | 68 (39 – 161) | 136 (72 - 312) | 90 (40 – 180) | 249 (125 – 394) | <0.001 |
<100 | 170 (30%) | 55 (62%) | 10 (37%) | 21 (54%) | 84 (20%) | <0.001 |
100-200 | 108 (19%) | 18 (20%) | 8 (30%) | 9 (23%) | 73 (18%) | 0.36 |
>200 | 289 (51%) | 16 (18%) | 9 (33%) | 9 (23%) | 255 (62%) | <0.001 |
Eligible for ART initiation3 | 288 (51%) | 79 (89%) | 22 (81%) | 30 (77%) | 157 (38%) | <0.001 |
TB test results | ||||||
AFB smear positive | 21 (3%) | 13 (14%) | 8 (29%) | 0 | 0 | 0.08 |
Low | 2 | 0 | 2 | |||
+ | 9 | 6 | 3 | |||
++ | 3 | 2 | 1 | |||
+++ | 7 | 5 | 2 | |||
M. tuberculosis culture | 124 (19%) | 96 (100%) | 28 (100%) | 0 | 0 | -- |
positive | ||||||
Urine LAM positive | 99 (15%) | 35 (37%) | 7 (25%) | 9 (23%) | 48 (10%) | <0.001 |