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Table 1 The comparative histopathological lesions of intestines between Crohn’s and Johne’s diseases

From: Prevalence of Mycobacterium avium subspecies paratuberculosis IS 900 DNA in biopsy tissues from patients with Crohn’s disease: histopathological and molecular comparison with Johne’s disease in Fars province of Iran

Lesions/diseases

CD

JD

N/30(%)

S

N/30(%)

S

Diffuse multibacillary granulomatous enteritis

0 (0%)

13 (43%)

+++

Diffuse granulomatous enteritis

6 (20%)

+

10 (33%)

++

Focal- multifocal granulomatous enteritis

19 (63%)

++

4 (14%)

+

lymphoplasmacytic enteritis

5 (17%)

+ +

3 (10%)

++

Lymphangiectasia/edema

20 (67%)

+++

29 (96%)

+++

Vasculitis/lymphangitis

6 (20%)

+

22 (73%)

+++

Lymphoid hyperplasia

10 (33%)

++

13 (43%)

++

Neuritis/neuronal hyperplasia

11 (36%)

++

13 (43%)

++

Cryptitis

12 (40%)

++

4 (14%)

+

Crypt abscesses

10 (33%)

++

3 (10%)

+

Ulceration

22 (73%)

+++

0

Fibrosis

16 (53%)

++

0

Pyloric gland metaplasia

12 (40%)

++

0

Thrombosis

9 (30%)

++

0

Paneth cell metaplasia/hyperplasia

5 (17%)

+

0

-

Goblet cell hyperplasia

4 (14%)

+

0

-

  1. JD Johne’s disease, CD Crohn’s disease, N Number, S Severity, +, mild, ++, moderate, +++, severe